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1.
Head Neck ; 38 Suppl 1: E2004-10, 2016 04.
Artigo em Inglês | MEDLINE | ID: mdl-26836036

RESUMO

BACKGROUND: The best treatment for advanced tongue tumors remains controversial. Total glossectomy with laryngeal preservation is considered a feasible option, despite its morbidity. METHODS: A retrospective analysis of 12 total glossectomies with laryngeal preservation was performed in order to assess the available reconstruction techniques and analyze survival and functional outcomes. RESULTS: One-year overall survival (OS) and disease-free survival (DFS) rates were 58.3% and 33.3%, respectively, both dropping to 25% after 3 years. Permanent gastrostomy was necessary in 10 patients, although videofluoroscopy revealed adequate tolerance to liquids. Speech intelligibility was satisfactory in 50% of the patients and severely impaired in the remaining 50%. CONCLUSION: Laryngeal preservation in the context of advanced tumors of the tongue without supraglottic invasion carried similar oncologic results to total glossectomy with laryngectomy, but offers a better phonatory function. However, it is usually associated with a higher gastrostomy dependency ratio. A scrupulous selection of candidates is mandatory. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2004-E2010, 2016.


Assuntos
Glossectomia , Neoplasias da Língua/cirurgia , Adulto , Idoso , Intervalo Livre de Doença , Feminino , Gastrostomia , Humanos , Laringe , Masculino , Pessoa de Meia-Idade , Tratamentos com Preservação do Órgão , Procedimentos de Cirurgia Plástica , Estudos Retrospectivos , Inteligibilidade da Fala , Taxa de Sobrevida
2.
Rev. esp. cir. oral maxilofac ; 34(3): 98-104, jul.-sept. 2012. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-102426

RESUMO

El ameloblastoma es un tumor odontogénico de estirpe epitelial. Aunque se clasifica como una tumoración benigna, suele ser localmente agresiva presentando elevada invasión local, con gran tendencia a la recidiva y con posibilidad metastásica ocasional. Se manifiesta preferentemente durante la tercera, cuarta y quinta décadas de la vida, sin predilección por razón de sexo, aunque puede darse en cualquier grupo de edad, incluidos los niños. Lamayoría de los ameloblastomas se encuentran sobre todo enmandíbula (al nivel del ángulo y rama). En el tratamiento se debe valorar su tipología clínica (sólido, multiquístico, uniquístico, mixto o periférico), su localización y el tamaño del tumor, así como la edad y las condiciones clínicas del paciente. Presentamos una revisión de los pacientes afectos de ameloblastomas tratados en nuestro Centro durante los últimos 10 años. Se aportan datos acerca de su aparición clínica, sus características histológicas, el manejo terapéutico realizado y analizamos el seguimiento y comparamos la aparición de recidivas en los pacientes presentados. Las características clínicas, incluso si se complementan con radiografías y/omuestras histológicas, no son siempre determinantes del comportamiento biológico y, por tanto tampoco lo son del pronóstico de un ameloblastoma individual(AU)


The ameloblastoma is an odontogenic tumour of epithelial origin. Although it is classified as benign, there is usually aggressive local invasion, a great tendency to recurrence, and occasional metastatic potential. It generally appears during the third, fourth and fifth decades of life, without gender predilection, although it can occur at any age, including in children. Ameloblastomas are mostly found in the mandible (angle and branch). In treatment, its clinical type (solid, unicystic, desmoplastic, mixed or peripheral), its location and size, must be assessed, as well as the age and clinical condition of the patient. We present a review of patients diagnosed and treated for ameloblastoma in our hospital during the last 10 years.We present data on clinical appearance, histological characteristics, and therapeutic management, and we analyse and compare the rate of recurrence in these patients. The clinical features, even if they are supplemented with radiographs and/or histological samples, are not always biological determinants of its behaviour, or of the individual prognosis of the ameloblastoma(AU)


Assuntos
Humanos , Masculino , Feminino , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Ameloblastoma/diagnóstico , Ameloblastoma/cirurgia , Tumor Odontogênico Escamoso/cirurgia , Radiografia Panorâmica/métodos , Radiografia Panorâmica , Ameloblastoma/fisiopatologia , Ameloblastoma , Mandíbula/patologia , Mandíbula/cirurgia , Mandíbula , Algoritmos , Estudos Retrospectivos
3.
Clin Nucl Med ; 36(4): 273-6, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21368599

RESUMO

The aim of this study was to evaluate the diagnostic efficacy of bone scintigraphy (BS) and radiolabeled white blood cell scintigraphy (WBCS) in detecting septic activity in the flat bones of the jaw. A retrospective analysis was conducted using 38 studies of combined BS plus WBCS: 33 of them 3-phase BS and 36 of them 2-phase WBCS. These studies were performed on 34 patients, 19 women and 15 men with a mean age of 56 years (22-79), who presented with suspected mandibular osteomyelitis, either acute or chronic exacerbation. The results were compared with histologic findings (55%) or with a minimum clinical/radiologic follow-up of 6 months (average, 21 months), when biopsy results were not available. BS showed a sensitivity of 100%, a specificity of 6.7%, a positive predictive value of 62%, and a negative predictive value of 100%. For WBCS, the corresponding values were as follows: 73.7%, 78.6%, 82%, and 69%. Accuracy was 63.2% for BS and 94.7% for WBCS. WBCS has proven to be a useful test for detecting septic activity in the jaw bone, being more effective than BS alone, which under certain circumstances, can return a very high false-positive rate.


Assuntos
Leucócitos/diagnóstico por imagem , Mandíbula/diagnóstico por imagem , Doenças Mandibulares/sangue , Doenças Mandibulares/diagnóstico por imagem , Osteomielite/sangue , Osteomielite/diagnóstico por imagem , Adulto , Idoso , Feminino , Humanos , Marcação por Isótopo , Masculino , Pessoa de Meia-Idade , Cintilografia , Estudos Retrospectivos , Fatores de Tempo , Adulto Jovem
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