One year clinical outcomes of renal artery stenting: the results of ODORI Registry.

The safety, efficacy and long term clinical benefits of renal artery revascularization by stenting are still a matter of debate. The aim of our study was to define the safety and efficacy of renal artery stenting with the Tsunami peripheral stent (Terumo Corporation, Tokyo, Japan). The ODORI was a prospective, multicentre registry which enrolled 251 consecutive patients, (276 renal arteries) in 36 centres across Europe. The primary endpoint was acute procedural success defined as <30% residual stenosis after stent placement. Secondary endpoints included major adverse events, blood pressure control, serum creatinine level, and target lesion revascularization (TLR) at 6 and 12 months. Patients were 70 +/- 10 years old, 59% were male, 33% had diabetes, and 96% hypertension. The main indications for renal stent implantation were hypertension in 83% and renal salvage in 39%. Direct stent implantation was performed in 76% of the cases. Acute success rate was 100% with residual stenosis of 2.5 +/- 5.4%. Systolic/diastolic blood pressure decreased from a mean of 171/89 at baseline to 142/78 mmHg at 6 months (p < 0.0001 vs. baseline), and 141/80 mmHg at 12 months (p < 0.0001 vs. baseline). Mean serum creatinine concentration did not change significantly in the total population. However, there was significant improvement in the highest tercile (from 283 micromol/l at baseline to 205 and 209 micromol/l at 6 and 12 months respectively). At 12-months, rates of restenosis and TLR were 6.6 and 0.8% respectively. The 12 month cumulative rate of all major clinical adverse events was 6.4% while the rate of device or procedure related events was 2.4%. In hypertensive patients with atherosclerotic renal artery stenosis Tsunami peripheral balloon-expandable stent provides a safe revascularization strategy, with a potential beneficial impact on hypertension control and renal function in the highest risk patients.

A new porcine sponge material for temporary embolization: an experimental short-term pilot study in swine.

PURPOSE: To evaluate the safety and efficacy of a porcine-derived gelfoam, Curaspon, for the temporary occlusion of the visceral arteries. METHODS: Curaspon was used for the selective embolization of segmentary hepatic, unilateral polar renal, and single lumbar arteries of 10 pigs under general anesthesia. Sequential angiographic checks were carried out and the pigs killed between 3 days and 2 weeks later. Macroscopic and microscopic studies using standard techniques were used to evaluate the immediate efficacy of embolization, duration of and completeness of recanalization on angiography, macroscopic appearance of target-organ ischemia, and microscopic analysis of inflammatory reaction. RESULTS: Immediate arterial occlusion was obtained in all cases. Renal arteries showed a total recanalization in 63% of cases on day 7 and 100% on day 14. Total hepatic recanalization was obtained in 100% of animals on day 7. All lumbar arteries were recanalized on day 14. Microscopic analysis in the kidney revealed a mild inflammatory reaction and a progressive lysis of the Curaspon (87% of samples at day 3 showed a persistence of Curaspon and 5% at day 14). In some cases, localized and partial destruction of the arterial wall was visualized. In the liver the same patterns were observed but resolved more completely and more rapidly. CONCLUSIONS: Curaspon is an efficient material for the temporary occlusion of visceral and parietal arteries in pigs. However, arterial aneurysms were observed and a relationship of these with the material cannot be excluded.

[Assessment of cardiac function by magnetic resonance and multislice spiral computed tomography]. / Evaluation de la fonction cardiaque en imagerie par résonance magnétique et scanner hélicoïdal multicoupe.

Magnetic resonance imaging and multislice spiral computed tomography are ideal techniques for assessing cardiac function. The main objectives of this article are to describe the different aspects, global and regional systolic left ventricular function, diastolic left ventricular function and right ventricular function, and to introduce the agreed parameters for this evaluation.

[Complications of myocardial infarction]. / Complications de l'infarctus du myocarde.

Most acute complications of myocardial infarction do not need emergency imaging, since they often result in death prior to hospital admission: ventricular fibrillation and tachycardia, papillary muscle or septal rupture, fissuration and tamponade. Imaging can play a role at distance of the acute phase (papillary muscle dysfunction, false aneurysm, development of a mural thrombus associated to left ventricular apical dyskinesis, with potential embolic complications).

Transient relief of abdominal angina by Wallstent placement into an occluded superior mesenteric artery.

A 56-year-old man presented with complete occlusion of the superior and inferior mesenteric arteries resulting in chronic mesenteric ischemia. After a minimal angioplasty a Wallstent was inserted across the superior mesenteric artery occlusion. This produced immediate clinical relief, with a successful angiographic result. Eight months later, an intrastent occlusion with acute bowel infarction was treated in emergency by saphenous vein bypass graft. Despite the death of the patient a few days later from a multivisceral failure syndrome, this method seemed to us feasible in treating a chronically occluded SMA in patients with high operative risk.

Relief of buttock claudication by percutaneous recanalization of an occluded superior gluteal artery.

We report a case of a woman presenting with right severe buttock claudication and normal neurological and osteoarticular examination, in whom a guidewire recanalization and percutaneous transluminal angioplasty (PTA) of an occluded right superior gluteal artery (SGA) has provided relief of her symptoms. To our knowledge, this is the first report of percutaneous recanalization of the SGA. PTA can be considered the treatment of choice for buttock claudication caused by SGA stenosis or occlusion.