1.
The Malaysian Journal of Pathology
; : 55-8, 2006.
Artigo
em Ml
| WPRIM (Pacífico Ocidental)
| ID: wpr-626709
RESUMO
Intense myelofibrosis is rarely associated with de novo acute myeloid leukaemia (AML) except in acute megakaryoblastic leukaemia (AML-M7) where there is diffuse marrow fibrosis as a consequence of proliferation of neoplastic myeloid cells. AML associated with significant myelofibrosis developing both de novo or secondary to primary (idiopathic) myelofibrosis is characterised by a fulminant course and extremely poor prognosis, primarily due to treatment-resistant disease. The prognostic value of degree of marrow fibrosis in de novo AML has been poorly investigated. We describe a case of extensive myelofibrosis associated with acute erythroblastic leukaemia (AML-M6) that responded to induction therapy of the leukaemia.
Assuntos
Mielofibrose Primária , Leucemia Mieloide Aguda
2.
Br J Haematol
; 116(4): 731, 2002 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11886374