RESUMO
The purpose of this study was to describe the clinical presentation, potential causative agents, treatment and outcome of febrile neutropenia (FN) in chemotherapy-treated cats. Medical records from eight institutions were retrospectively reviewed. A total of 22 FN events in 20 cats were evaluated. Lymphoma was the most common cancer diagnosis; lomustine and vinca alkaloids were the most frequently implicated causative agents. Presenting clinical signs included decreased appetite, lethargy, vomiting and diarrhoea. Median body temperature and absolute neutrophil count at presentation were 104.1 °F; 40 °C (range: 103.1-105.1 °F; 39.5-40.6 °C) and 246 mL-1 (range: 0-1600 mL-1 ), respectively. Median number of days between chemotherapy administration and FN onset was 5 (range: 4-25 days). All but one cat were treated with intravenous fluids and broad spectrum antibiotics. Fevers resolved in all cases and absolute neutrophil counts returned to normal in 19 cats. Clinical presentation of cats with FN appears similar to that of dogs.
Assuntos
Antineoplásicos/efeitos adversos , Doenças do Gato/induzido quimicamente , Neutropenia Febril/veterinária , Animais , Antineoplásicos/uso terapêutico , Doenças do Gato/tratamento farmacológico , Gatos , Neutropenia Febril/induzido quimicamente , Feminino , Contagem de Leucócitos/veterinária , Lomustina/efeitos adversos , Lomustina/uso terapêutico , Linfoma/tratamento farmacológico , Linfoma/veterinária , Masculino , Estudos Retrospectivos , Alcaloides de Vinca/efeitos adversos , Alcaloides de Vinca/uso terapêuticoRESUMO
A 9-year-old, quarter horse gelding with obstructive urethrolithiasis was treated with a perineal urethrostomy. The horse's condition deteriorated and abdominocentesis confirmed septic uroperitonitis. The horse was euthanized and postmortem examination revealed peritonitis, a tear in the lateral wall of the bladder, and a nephrolith within the left renal pelvis.
