Psychoanalysis and Affective Neuroscience. The Motivational/Emotional System of Aggression in Human Relations.

This article highlights the evolutionary biological epistemology in Freud psychoanalytic theory. The concepts of aggressive and sexual drives are cornerstones of the psychoanalytic epistemological system, concerning the motivational/emotional roots of mental functioning. These biological roots of mental functioning, especially with regard to aggressive drive, have gradually faded away from psychoanalytic epistemology, as we show in this article. Currently, however, Neurosciences, and in particular Affective Neuroscience (Panksepp, 1998), can help us to have a better understanding of the biological roots of human mental functioning. The motivational/emotional systems studied by Affective Neuroscience can give a new epistemological foundation to the aggressive drive concept in psychoanalytic theory. Over the course of human evolution, motivational/emotional systems have played a role in social relationships and also in mental functioning. In this regard, among the various types of aggression (ANGER in Panksepp taxonomy 1998) that we consider in our article, inter-male aggression, also named Dominance motivational/emotional system, is that which regulates social interactions between sexually matured adults. This type of aggression acts in complementary connection with FEAR motivational/emotional system that regulate submissive behavior and social defeat, and the latter one is of the more important stressors. The interaction between aggression and FEAR motivational/emotional systems gives rise to agonistic behavior or dominance/submission motivational/emotional system, as we propose in our article. There is now a large literature that identifies in the dynamic of Competitive behavior, which is one of the main factors of mental illness. When social interactions activate the competitive behavior, the subject can perceive himself as "destined to victory" or "destined to defeat," activating either behaviors or emotions connected to the Involuntary Defeat Strategy or Involuntary Dominant Strategy (Sloman, 2002), which we can find in many types of mental disorders, for example, mood disorders or anxiety disorders.

A more in-depth interpretation of MMPI-2 in MS patients by using Harris and Lingoes subscales.

Multiple Sclerosis (MS) is frequently associated with neuropsychiatric abnormalities. The aim of our study was to discriminate between psychosomatic disturbances and MS physically-related symptoms using the Harris-Lingoes subscales of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2). Forty-six MS out-patients (35 females; mean age = 44.5); and 82 healthy volunteers (62 females; mean age = 46.5) were evaluated with MMPI-2 questionnaire. The frequency distribution of MMPI-2 clinical scales with high scores (> = 65) and the related Harris-Lingoes subscales were analyzed for both MS patients and healthy control subjects. Data analysis showed elevated scores in 47.8% of the patients mainly on MMPI-2 clinical scales 1, 2, and 3. The Harris-Lingoes subscales analysis allowed us to isolate and identify physical symptoms contributing to elevation of MMPI-2 clinical scales, reduce the occurrence of false positives (MMPI-2 clinical scales elevations mainly due to MS physical disability) and provide a more detailed description of psycho-emotional symptoms of MS patients. In conclusion, our study shows the utility of Harris-Lingoes subscales analysis when MMPI-2 is used for psychological assessment of MS patients.

Obsessive-Compulsive Tendencies, Self/Other Perception, Personality, and Suicidal Ideation in a Non-clinical Sample.

Research on the risk factors for SI in adults with OC tendencies is limited, and it is still unclear whether the association between OC tendencies and SI in non-clinical individuals exists. The goal of the present study was to test the associations between OC tendencies, self/other perception, personality traits, depressive symptoms and SI among a non-clinical adult population. We investigated an Italian sample of 337 adults, who were administered a set of self-report questionnaires to assess obsessive-compulsive tendencies, depression, self/other perception, personality traits, and hopelessness. Confirmatory factor analyses (CFA) were performed. In the final model we found that personality, obsessive-compulsive factor and suicidal ideation were significantly correlated with each other: personality correlated negatively with obsessive-compulsive factor and suicidal ideation, while obsessive-compulsive factor and suicidal ideation resulted as strongly positively associated. Our results highlight the importance of assessing OC tendencies, negative self/other perception and SI. Understanding their role and interplay will allow for the development and implementation of more advanced prevention and treatment policies.

Treatment Decision-Making Capacity in Children and Adolescents Hospitalized for an Acute Mental Disorder: The Role of Cognitive Functioning and Psychiatric Symptoms.

OBJECTIVE: This study was conducted to assess treatment decision-making capacity (TDMC) in a child and adolescent psychiatric sample and to verify possible associations between TDMC, psychiatric symptom severity, and cognitive functioning. METHODS: Twenty-two consecutively recruited patients hospitalized for an acute mental disorder, aged 11-18 years, underwent measurement of TDMC by the MacArthur Competence Assessment Tool for Treatment (MacCAT-T). The MacCAT-T interview focused on patients' current treatment, which comprised second-generation antipsychotics (45.5%), first-generation antipsychotics (13.6%), antiepileptic drugs used as mood stabilizers or lithium carbonate (45.5%), selective serotonin reuptake inhibitors (32%), and benzodiazepines (18%). We moreover measured cognitive functioning (Wechsler Intelligence Scale for Children III) and psychiatric symptom severity (Brief Psychiatric Rating Scale v 4.0). RESULTS: Patients' TDMC varied within the sample, but MacCAT-T scores were good in the sample overall, suggesting that children and adolescents with severe mental disorders could be competent to consent to treatment. The TDMC proved independent of psychiatric diagnosis while being positively associated with cognitive functioning and negatively with excitement. CONCLUSION: The MacCAT-T proved feasible for measuring TDMC in a child and adolescent psychiatric sample. TDMC in minors with severe mental disorders was not necessarily impaired. These results deserve reconsidering the interplay between minors and surrogate decision-makers as concerning treatment decisions.

Brain Emotion Systems, Personality, Hopelessness, Self/Other Perception, and Gambling Cognition: A Structural Equation Model.

The aim of this study was to explore the relations between gambling, brain emotion systems, personality, self/other perception, and hopelessness in an Italian community. Dimensions of gambling, positive and negative emotions, self/other perception, personality and hopelessness were assessed in a community sample of 235 adults aged 19-59 years. Two structural models were tested. We found a significant correlation between problem gambling and impulsivity, which in association with aggressivity and negative personality dimensions may help explain the psychopathology factor, i.e. a latent variable involving neurotic personality, hopelessness, high sensation seeking, low metacognitive responsiveness, and disorganized patterns of interpersonal relationships. These results contribute to develop a theoretical framework of gambling in relation with personality factors and provide a new approach for clinical intervention of problem gambling that relies on a solid multidimensional perspective.

Factor structure and psychometric properties of the Italian version of the Gambling Related Cognitions Scale (GRCS-I).

The past decade has witnessed an expanded accessibility and popularity of gambling worldwide, and in Italy the phenomenon significantly increased. Nevertheless, little is known about the role of gambling cognitions among Italian individuals, and few scales assessing problem gambling have been validated. The purpose of the present study was to examine and validate the Gambling Related Cognitions Scale-Italian version (GRCS-I), based on the 23-item Gambling Related Cognitions Scale (GRCS). Two-tailed t tests, ANOVA, MANOVA, Pearson's correlation, and multiple regression analyses were used for continuous variables, while χ(2) tests with Yates's correction for categorical variables. Cronbach's α was utilized to determine the internal consistency, and logistic regression analysis and the receiver operating characteristic curve analysis to determine discriminant validity. Principal axis factoring with Oblimin rotation was applied, and then confirmatory factor analysis was used to cross-validate the factor structures. We extracted a five-factor solution that accounted for 60 % of variance. All 23 items had communalities and factor loadings were satisfactory, and the factor structures were similar to the original version of the measure. The Cronbach's α coefficients were adequate, and concurrent and discriminant validities of the GRCS were also confirmed. GRCS-I presented good psychometric properties and it demonstrated good validity and reliability, providing a valid and suitable tool for the assessment of gambling related cognitions among Italian individuals.

Executive functions, impulsivity, and inhibitory control in adolescents: A structural equation model.

Background. Adolescence represents a critical period for brain development, addressed by neurodevelopmental models to frontal, subcortical-limbic, and striatal activation, a pattern associated with rise of impulsivity and deficits in inhibitory control. The present study aimed at studying the association between self-report measures of impulsivity and inhibitory control with executive function in adolescents, employing structural equation modeling. Method. Tests were administered to 434 high school students. Acting without thinking was measured through the Barratt Impulsiveness Scale and the Dickman Impulsivity Inventory, reward sensitivity through the Behavioral Activation System, and sensation seeking through the Zuckerman-Kuhlman-Aluja Personali- ty Questionnaire. Inhibitory control was assessed through the Behavioral Inhibition System. The performance at the Wisconsin Card Sorting Task indicated executive function. Three models were specified using Sample Covariance Matrix, and the estimated parameters using Maximum Likelihood. Results. In the final model, impulsivity and inhibitory control predicted executive function, but sensation seeking did not. The fit of the model to data was excellent. Conclusions. The hypothesis that inhibitory control and impulsivity are predictors of executive function was supported. Our results appear informative of the validity of self-report measures to examine the relation between impulsivity traits rather than others to regulatory function of cognition and behavior.

Self/other Perception Mediates Between Personality and Suicidal Ideation in Young Adults

Background and Objectives: Individual differences in vulnerability to suicidal ideation have been recently addressed to internal working models of attachment. However, to date, research has mainly focused on adolescents. Few studies have investigated the role of adult attachment and personality dimensions in suicidal ideation, either examined from a mediational perspective. In this study, we aimed at testing a theoretical model in which Self/other perception mediates between personality and suicidal ideation in young adults. Methods: Dimensions of Attachment (self/other perception), Personality (the Big Five factor model), and Suicidal Ideation (hopelessness and depression) were assessed in a community sample of 319 young adults from Northern Italy. Structural Equation Modeling and mediation analysis were conducted. Controlling for demographic variables (i.e., gender, age, education, and job), we tested three structural models. Results: The final model confirmed our hypothesis that self/other perception mediates between personality (high neuroticism and low extraversion) and suicidal ideation, providing excellent fit to data. Conclusions: In line with the conceptual framework of the Attachment Theory, findings suggest that failure to resolve attachment-related distress is related to the emergence of negative self/other models in adults. Such internal models are likely to attenuate the association between neuroticism and extraversion with depressive symptoms, hopelessness and suicidal ideation (AU)

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Personality and suicidal ideation in the elderly: factorial invariance and latent means structures across age.

OBJECTIVES: Suicide among the elderly is a dramatic global health problem. Although fatal attempts are frequent in the elderly, research indicated that they rarely present long-term elaboration of suicidal ideation and communicate their intents. Consequently, risk factor detection and assessment are salient. Although evidence on the association between personality and suicidal ideation in young adults is accumulating, little is known about its relevance in the elderly. The purpose of the present study was to analyze the components of a measurement model that are invariant across young adults and older adults and then investigate the relations among dimensions of personality and suicide risk. We postulated a specific relation pattern a priori and tested the hypotheses statistically in order to examine the models for equivalency of the factorial measurement. METHOD: We investigated 316 young adults and 339 older adults, who were administered self-report questionnaires to assess depression, hopelessness, alternative five-factor model of personality, and self-other perception. RESULTS: Multigroup confirmatory factor analyses were conducted, yielding a final model with excellent fit to the data. This model showed a similar pattern of associations between suicidal ideation and personality across both groups. CONCLUSIONS: Although the elderly are exposed to specific life stressors associated with suicidal ideation, our findings suggest that the elderly and young adults may be similar on personality and psychopathology variables predicting suicidal ideation than previously hypothesized. Implications are provided for enhanced assessment and intervention of the elderly high in neuroticism, depression, hopelessness, and with negative self-other perception.

Validity of criteria-based content analysis (CBCA) at trial in free-narrative interviews.

OBJECTIVE: The reliability of child witness testimony in sexual abuse cases is often controversial, and few tools are available. Criteria-Based Content Analysis (CBCA) is a widely used instrument for evaluating psychological credibility in cases of suspected child sexual abuse. Only few studies have evaluated CBCA scores in children suspected of being sexually abused. We designed this study to investigate the reliability of CBCA in discriminating allegations of child sexual abuse during court hearings, by comparing CBCA results with the court's final, unappealable sentence. We then investigated whether CBCA scores correlated with age, and whether some criteria were better than others in distinguishing cases of confirmed and unconfirmed abuse. METHODS: From a pool of 487 child sexual abuse cases, confirmed and unconfirmed cases were selected using various criteria including child IQ≥70, agreement between the final trial outcome and the opinion of 3 experts, presence of at least 1 independent validating informative component in cases of confirmed abuse, and absence of suggestive questions during the child's testimonies. This screening yielded a study sample of 60 confirmed and 49 unconfirmed cases. The 14 item version of CBCA was applied to child witness testimony by 2 expert raters. RESULTS: Of the 14 criteria tested, 12 achieved satisfactory inter-rater agreement (Maxwell's Random Error). Analyses of covariance, with case group (confirmed vs. unconfirmed) and gender as independent variables and age as a covariate, showed no main effect of gender. Analyses of the interaction showed that the simple effects of abuse were significant in both sex. Nine CBCA criteria were satisfied more often among confirmed than unconfirmed cases; seven criteria increased with age. CONCLUSION: CBCA scores distinguish between confirmed and unconfirmed cases. The criteria that distinguish best between the 2 groups are Quantity of Details, Interactions, and Subjective Experience. CBCA scores correlate positively with age, and independently from abuse; all the criteria test except 2 (Unusual Details and Misunderstood Details) increase with age. The agreement rate could be increased by merging criteria Unusual and Superfluous details that achieve a low inter-rater agreement when investigated separately. PRACTICE IMPLICATION: Given its ability to distinguish between confirmed and unconfirmed cases of suspected child abuse, the CBCA could be a useful tool for expert opinion. Because our strict selection criteria make it difficult to generalize our results, further studies should investigate whether the CBCA is equally useful in the cases we excluded from our study (for example mental retardation).

Slow EEG amplitude oscillations during NREM sleep and reading disabilities in children with dyslexia.

STUDY OBJECTIVES: To analyze non-rapid eye movement (NREM) sleep microstructure of children with dyslexia, by means of cyclic alternating pattern (CAP) analysis and to correlate CAP parameters with neuropsychological measures. DESIGN: Cross-sectional study using polysomnographic recordings and neuropsychological assessments. SETTING: Sleep laboratory in academic center. PARTICIPANTS: Sixteen subjects with developmental dyslexia (mean age 10.8 years) and 11 normally reading children (mean age 10.1 years) underwent overnight polysomnographic recording. INTERVENTION: N/A. MEASUREMENTS AND RESULTS: Sleep architecture parameters only showed some statistically significant differences: number of sleep stage shifts per hour of sleep, percentage of N3, and number of R periods were significantly lower in dyslexic children versus controls. CAP analysis revealed a higher total CAP rate and A1 index in stage N3. A2% and A2 index in stage N2 and N3 were lower in dyslexic children while no differences were found for A3 CAP subtypes. The correlation analysis between CAP parameters and cognitive-behavioral measures showed a significant positive correlation between A1 index in N3 with Verbal IQ, full-scale IQ, and Memory and Learning Transfer reading test; while CAP rate in N3 was positively correlated with verbal IQ. CONCLUSIONS: To overcome reading difficulties, dyslexic subjects overactivate thalamocortical and hippocampal circuitry to transfer information between cortical posterior and anterior areas. The overactivation of the ancillary frontal areas could account for the CAP rate modifications and mainly for the increase of CAP rate and of A1 index in N3 that seem to be correlated with IQ and reading abilities.