Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Gene ; 926: 148608, 2024 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-38823655

RESUMO

During the COVID-19 pandemic, the SARS-CoV-2 gene mutation has been rapidly emerging and spreading all over the world. Experts worldwide regularly monitor genetic mutations and variants through genome-sequence-based surveillance, laboratory testing, outbreak investigation, and epidemiological probing. Clinical pathologists and medical laboratory scientists prefer developing or endorsing COVID-19 vaccines with a broader immune response involving various antibodies and cells to protect against mutations or new variants. Randomness plays an enormous role in pathology and epidemiology. Hence, based on epidemiological parameter data, we construct and probe a stochastically perturbed dominant variant of the coronavirus epidemic model with three nonlinear saturated incidence rates. We reveal the existence of a unique global positive solution to the constructed stochastic COVID-19 model. The Lyapunov function method is used to determine the presence of a stationary distribution of positive solutions. We derive sufficient conditions for the coronavirus to be eradicated. Eventually, numerical simulations validate the effectiveness of our theoretical outcomes.


Assuntos
COVID-19 , SARS-CoV-2 , COVID-19/epidemiologia , COVID-19/virologia , COVID-19/genética , Humanos , SARS-CoV-2/genética , Pandemias , Processos Estocásticos , Mutação , Simulação por Computador , Modelos Epidemiológicos
2.
Int J Dyn Control ; 11(1): 122-135, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35756149

RESUMO

Several studies have previously been conducted on the dynamics of probabilistic epidemic models driven by Lévy disorder. All of these works have used the Poisson counting process with finite Lévy measures. However, this scope disregards a considerable category of correlated Lévy jump processes governed by an infinite Lévy measure. In this research, we take into consideration this general framework applied to an epidemic model with a quarantine strategy. Under an appropriate hypothetical setting, we infer the exact threshold value between the ergodicity and the disease disappearance. Our analysis completes the work presented by Privault and Wang (J Nonlinear Sci 31(1):1-28, 2021) and puts forward a novel analytical aspect to deal with other stochastic models in several areas. As a numerical application, we implement the algorithm of Rosinski (Stoch Process Appl 117:677-707, 2007) for tempered stable Lévy processes with an infinite Lévy measure.

3.
Chaos Solitons Fractals ; 159: 112110, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35502416

RESUMO

This study concentrates on the analysis of a stochastic SIC epidemic system with an enhanced and general perturbation. Given the intricacy of some impulses caused by external disturbances, we integrate the quadratic Lévy noise into our model. We assort the long-run behavior of a perturbed SIC epidemic model presented in the form of a system of stochastic differential equations driven by second-order jumps. By ameliorating the hypotheses and using some new analytical techniques, we find the exact threshold value between extinction and ergodicity (persistence) of our system. The idea and analysis used in this paper generalize the work of N. T. Dieu et al. (2020), and offer an innovative approach to dealing with other random population models. Comparing our results with those of previous studies reveals that quadratic jump-diffusion has no impact on the threshold value, but it remarkably influences the dynamics of the infection and may worsen the pandemic situation. In order to illustrate this comparison and confirm our analysis, we perform numerical simulations with some real data of COVID-19 in Morocco. Furthermore, we arrive at the following results: (i) the time average of the different classes depends on the intensity of the noise (ii) the quadratic noise has a negative effect on disease duration (iii) the stationary density function of the population abruptly changes its shape at some values of the noise intensity. Mathematics Subject Classification 2020: 34A26; 34A12; 92D30; 37C10; 60H30; 60H10.

4.
Math Biosci Eng ; 19(12): 13560-13581, 2022 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-36654058

RESUMO

Monkeypox 2022, a new re-emerging disease, is caused by the Monkeypox virus. Structurally, this virus is related to the smallpox virus and infects the host in a similar way; however, the symptoms of Monkeypox are more severe. In this research work, a mathematical model for understanding the dynamics of Monkeypox 2022 is suggested that takes into account two modes of transmission: horizontal human dissemination and cross-infection between animals and humans. Due to lack of substantial knowledge about the virus diffusion and the effect of external perturbations, the model is extended to the probabilistic formulation with Lévy jumps. The proposed model is a two block compartmental system that requires the form of Itô-Lévy stochastic differential equations. Based on some assumptions and nonstandard analytical techniques, two principal asymptotic properties are proved: the eradication and continuation in the mean of Monkeypox 2022. The outcomes of the study reveals that the dynamical behavior of the proposed Monkeypox 2022 system is chiefly governed by some parameters that are precisely correlated with the noise intensities. To support the obtained theoretical finding, examples based on numerical simulations and real data are presented at the end of the study. The numerical simulations also exhibit the impact of the innovative adopted mathematical techniques on the findings of this work.


Assuntos
Epidemias , Mpox , Varíola , Animais , Humanos , Mpox/epidemiologia , Monkeypox virus , Modelos Teóricos , Difusão , Varíola/epidemiologia
5.
Comput Math Methods Med ; 2020: 9676501, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32411288

RESUMO

Hepatitis B epidemic was and is still a rich subject that sparks the interest of epidemiological researchers. The dynamics of this epidemic is often modeled by a system with constant parameters. In reality, the parameters associated with the Hepatitis B model are not certain, but the interval in which it belongs to can readily be determined. Our paper focuses on an imprecise Hepatitis B model perturbed by Lévy noise due to unexpected environmental disturbances. This model has a global positive solution. Under an appropriate assumption, we prove the existence of a unique ergodic stationary distribution by using the mutually exclusive possibilities lemma demonstrated by Stettner in 1986. Our main effort is to establish an almost perfect condition for the existence of the stationary distribution. Numerical simulations are introduced to illustrate the analytical results.


Assuntos
Hepatite B/epidemiologia , Modelos Biológicos , Algoritmos , Biologia Computacional , Simulação por Computador , Epidemias/estatística & dados numéricos , Hepatite B/transmissão , Humanos , Conceitos Matemáticos , Modelos Estatísticos , Distribuição de Poisson , Probabilidade , Processos Estocásticos , Biologia de Sistemas
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...