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1.
Cureus ; 14(8): e28430, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36176882

RESUMO

INTRODUCTION: Formulation of various preventive and therapeutic strategies is possible only by a better understanding of the immune-inflammatory profile of peri-implant diseases. For understanding the changes and turnover of bone, various markers have been used in the past literature, out of which, N-telopeptide of Type I Collagen (NTx) is acknowledged to be the most reliable marker. AIMS AND OBJECTIVES: Assessment of calprotectin and NTx concentration in gingival crevicular fluid (GCF) around the implant sites in subjects suffering from peri-implantitis. MATERIALS AND METHODS: In total, 70 healthy individuals were included in the present study. These patients had opted for dental implants within the last decade. After collecting the peri-implant crevicular fluid (PICF) and GCF, various examinations were carried out. PICF samples were obtained with the help of sterile paper available in the form of strips. The enzyme-linked immunosorbent assay (ELISA) technique was used for measuring the calprotectin and NTx. All the readings were obtained in nanograms per microliter of PICF. All the results were recorded and analyzed. RESULTS: The overall mean calprotectin and NTx values were observed to be in a significantly higher range within the sites suffering from peri-implantitis when compared with healthy locations. The calprotectin values and NTx levels were positively correlated with the mean values of periodontal parameters observed clinically. CONCLUSION: Both calprotectin and NTx could be used as a biomarker signifying the presence of inflammation as well as bone resorption in patients suffering from peri-implantitis.

2.
J Pharm Bioallied Sci ; 13(Suppl 1): S187-S189, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34447072

RESUMO

BACKGROUND: The present study was undertaken for assessing the pattern of oral prosthetic treatment and prevalence of dental diseases in edentulous patients in North Indian population. MATERIALS AND METHODS: A survey was carried out in North Indian population, and screening of the edentulous patients was done. Five hundred edentulous patients were enrolled. Complete oral and general examination was carried out. Pro forma was framed, and clinical details were recorded. Using mouth mirror and explorer, complete oral examination was carried out. Demographic profile was also evaluated. Prosthetic rehabilitation pattern of all the participants was also recorded. RESULTS: Complete removable denture and removable partial denture were method of rehabilitation in 28% and 31% of the participants. Dental implant-supported complete denture was used in 8% of the patients, whereas dental implant-supported overdenture was used in 33% of the participants. Ulcerative lesions were present in 5% of the patients, whereas oral leukoplakia was present in 4% of the patients. Oral lichen planus and torus were present in 2% and 1% of the patients. CONCLUSION: Majority of the geriatric patients prefer having removable denture. Furthermore, due to nutritional deficiency associated with geriatric age, oral leukoplakia and ulcerative lesions are more common in them.

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