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1.
Acta Neurochir (Wien) ; 166(1): 248, 2024 Jun 04.
Artigo em Inglês | MEDLINE | ID: mdl-38833175

RESUMO

INTRODUCTION: An increasingly ageing population presents emerging healthcare challenges. Adequate clinical evaluation and understanding of outcome-predicting factors are integral to delivering safe spinal surgery to super-elderly patients. AIM: To evaluate spine surgery outcomes in patients aged 80 or above. METHODS: We retrospectively evaluated patients 80 years and above who underwent elective or emergency spinal surgery between 2017 and 2022. The Eurospine Surgery Classification (ESC) was used to classify operations into Large, Medium, and Small. We calculated and compared Clinical Frailty Scores (CFS) pre- and post-operatively. RESULTS: Two hundred forty-five patients met the inclusion criteria. Most were male (n = 145). The age range was 80 to 99 (mean 83.3). Most operations were elective (n = 151, 62%). In our cohort, 211, 22, 10,2 and 1 patients had degenerative, trauma, tumour, infective and vascular pathologies, respectively. According to the Eurospine classification, 201 (82.0%) had Minor spine surgery (63 emergently and 138 electively), 38 had Medium surgery (15.5% - 30 emergently and 8 electively), and 6 had Large surgery (2.4% - 1 emergently and 5 electively). 163 (66.5%) were discharged or under follow-up. There were 11 in-patient mortalities (4.5%). Outpatient mortality was 51 (20.8%), with the median time from surgery to death being 504.5 days, all the outpatient mortalities were neither non-spinal pathology nor spinal surgical related. CFS improved across the cohort, from 5 pre-operatively to 4 post-operatively (p < 0.001). CONCLUSION: Spine surgery in those over the 80s can be performed safely and improve their quality of life, as demonstrated by improvements in the CFS. Good patient selection and adequate pre-operative workup is essential, although it may not be possible in emergencies.


Assuntos
Doenças da Coluna Vertebral , Humanos , Masculino , Estudos Retrospectivos , Feminino , Idoso de 80 Anos ou mais , Doenças da Coluna Vertebral/cirurgia , Medição de Risco/métodos , Procedimentos Cirúrgicos Eletivos/métodos , Complicações Pós-Operatórias/epidemiologia , Estudos de Coortes , Coluna Vertebral/cirurgia , Resultado do Tratamento , Procedimentos Neurocirúrgicos/métodos
2.
Childs Nerv Syst ; 40(5): 1449-1454, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38217729

RESUMO

INTRODUCTION: Chiari 1 malformation and hind brain hernia can be associated with skull base and craniocervical anomalies. One of the more recently associated anomalies is a retroverted or retroflexed odontoid process or dens. We conducted a retrospective study of our operated symptomatic and conservatively managed asymptomatic Chiari cohort to assess the impact of dens retroflexion on rate of revision or cerebrospinal fluid diversion following primary foramen magnum decompression (FMD). METHODS: We undertook a retrospective study of all foramen magnum decompression (FMD) cases for Chiari type 1 malformation performed over a 15-year period in a single tertiary paediatric neurosurgical unit. For comparison, non-operated asymptomatic Chiari cases were considered as reference cohort. Information gathered included: demographics, age, sex, length of cerebellar tonsils below McRae's line, pB-C2 distance (a line drawn perpendicular to one drawn between the basion and the posterior aspect of the C2 body), angle of retroflexion (angle formed between a line drawn through the odontoid synchondrosis and its intersection with a line drawn from the tip of the odontoid process) and angle of retroversion (angle formed between the line drawn from the base of C2 and its intersection with a line drawn from the tip of the odontoid process). Grade of retroflexion was measured using pre-operative mid-sagittal MR images and classified as grade 0 (> 90°), grade 1 (85°-89°); grade 2 (80°-84°) and grade 3 (< 80°). The rates for redo surgery or need for cerebrospinal fluid (CSF) diversion were obtained from clinical records and compared in the operated and non-operated groups. RESULTS: One hundred twenty-six Chiari 1 patients were included in this study with adequate imaging. Sixty-five patients were in the non-operated asymptomatic cohort with 61 patients in the operated symptomatic cohort. Mean age of non-operated cohort was 10.2 years with M:F ratio (30:35). Mean cerebellar tonsillar length below McRae's line was 10.3 mm. 7.7% of this cohort had associated syrinx. Mean angles of retroversion and retroflexion were 76 and 78°, respectively. Retroflexion grades included (9.2% grade 1, 35% grade 2 and 52.3% grade 3). pB-C2 distance was 6.8 mm. Mean age of operated cohort was 11.3 years, with M:F ratio (21:40). Mean cerebellar tonsillar length below McRae's line was 15 mm. 45.9% of this cohort had associated syrinx. Mean angles of retroversion and retroflexion were 73 and 74.5°, respectively. Retroflexion grades included (4.9% grade 1, 16.5% grade 2 and 78.6% grade 3). pB-C2 distance was 6.9 mm. No association was identified between retroflexion grade and rate of revision or CSF diversion following primary foramen magnum decompression. CONCLUSION: The operated Chiari 1 cohort had more retroflexed dens, longer tonsils and associated syrinx compared to the non-operated asymptomatic cohort.


Assuntos
Malformação de Arnold-Chiari , Siringomielia , Criança , Humanos , Estudos Retrospectivos , Malformação de Arnold-Chiari/cirurgia , Forame Magno/cirurgia , Imageamento por Ressonância Magnética , Descompressão Cirúrgica/métodos , Siringomielia/cirurgia
3.
Oxf Med Case Reports ; 2014(5): 96-7, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25988042

RESUMO

In April 1999, a 25-year-old male underwent magnetic resonance imaging (MRI) as a control subject for a multiple sclerosis study. The scan serendipitously revealed two lesions ('incidentalomas') in the right frontal lobe. Initially, he was asymptomatic and was monitored with interval MRI scans. After years of monitoring, contact was accidentally lost. He later presented following a witnessed generalized seizure. He was commenced on phenytoin, which was changed to carbamazepine due to side effects. MRI revealed three gliomas and an open brain biopsy confirmed a diagnosis of low-grade astrocytoma. The location and multifocal nature of the gliomas ruled out complete neurosurgical debulking. However, his seizures increased in frequency and in February 2007, the biopsy confirmed malignant transformation to multifocal glioblastoma multiforme. He successfully underwent partial debulking, radiotherapy and adjuvant temozolomide chemotherapy. Currently, he is 6 years post-treatment and asymptomatic.

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