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1.
Int J STD AIDS ; 19(8): 557-8, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18663045

RESUMO

Mental health issues following sexual assault in young people are common but early intervention may improve outcome. A retrospective case-note review of 58 female patients aged between 13 and 18 attending The Haven Whitechapel, a sexual assault referral centre, demonstrated past emotional problems in 72% of those seen, and current emotional problems in 95% of those being followed up. Fifteen percent were already involved with adolescent mental health services (AMHS). All patients requiring and not already receiving input were referred to AMHS or in-house. Of 23 patients referred to AMHS, eight (35%) were accepted and the patients attended, seven (30%) were accepted but did not attend, six (26%) were declined and the outcome of two referrals was unknown. The prevalence of emotional problems and inconsistent referral outcomes demonstrate a need for closer links with AMHS, clearer referral criteria and improved referral pathways.


Assuntos
Serviços de Saúde do Adolescente , Transtornos Mentais/epidemiologia , Serviços de Saúde Mental , Encaminhamento e Consulta , Delitos Sexuais , Adolescente , Serviços de Saúde do Adolescente/estatística & dados numéricos , Humanos , Transtornos Mentais/etiologia , Transtornos Mentais/terapia , Serviços de Saúde Mental/estatística & dados numéricos , Prevalência , Encaminhamento e Consulta/estatística & dados numéricos , Delitos Sexuais/psicologia
2.
J Hand Surg Am ; 12(2): 240-5, 1987 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-3559078

RESUMO

Inadvertent intra-arterial injection of drugs produces a well-defined clinical syndrome whose pathophysiology remains unclear. This study was designed to determine the role of the inflammatory mediator, thromboxane, in intra-arterial drug injections. The rabbit ear model, as described by Kinmonth and Sheppard, was used. Five of the experimental groups were treated with specific or nonspecific thromboxane blocking agents and two groups served as controls. Immunohistochemical staining of the control ears showed elevated levels of thromboxane within the first 6 hours postinjury. The specific thromboxane blocking agents, methimazole and Aloe vera, showed almost complete blockade of thromboxane production. The percentage of ear survival was significantly greater in the group treated with topical Aloe vera (p less than 0.05) and even greater survival was achieved in the combined Aloe vera/methimazole group (p less than 0.01). On the basis of these results, we have begun treatment of such injuries with specific and nonspecific thromboxane blocking agents.


Assuntos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos , Injeções Intra-Arteriais/efeitos adversos , Tromboxanos/fisiologia , Animais , Modelos Animais de Doenças , Orelha/irrigação sanguínea , Preparações Farmacêuticas/administração & dosagem , Coelhos , Tiopental/toxicidade , Tromboxanos/antagonistas & inibidores
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