1.
Appl Environ Microbiol
; 47(5): 1167-8, 1984 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6742831
RESUMO
Germfree rats biosynthetize cholic and beta-muricholic acids. The latter does not exist in humans. Germfree rats were given human fecal suspensions. These rats degraded cholic acid into deoxycholic acid but failed to metabolize beta-muricholic acid.
Assuntos
Bactérias/metabolismo , Ácidos Cólicos/metabolismo , Sistema Digestório/microbiologia , Fezes/microbiologia , Animais , Biotransformação , Ácido Cólico , Cromatografia Gasosa , Ácido Desoxicólico/biossíntese , Sistema Digestório/metabolismo , Feminino , Vida Livre de Germes , Humanos , Masculino , Ratos
2.
Appl Environ Microbiol
; 37(6): 1127-31, 1979 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-485143
RESUMO
In the feces of conventional rats, the amount of omega-muricholic and hyodeoxycholic acids vary according to the diet. To understand this phenomenon, we investigated the bacterial formation of these bile acids. The present paper reports the first isolation, from conventional rat feces, of a strain of Clostridium group III which transforms beta-muricholic acid, the main bile acid in germfree rats, into omega-muricholic acid.
