Three-dimensional volume and shape of the infrapatellar fat pad during quasi-static knee extension from 30° to 0°: comparisons of patients with osteoarthritic knees and young, healthy individuals.

[Purpose] Previous studies suggest that the infrapatellar-fat-pad is affected by aging or knee osteoarthritis, and that the infrapatellar-fat-pad in knee osteoarthritis cases may be associated with limited mobility during knee movement. This study aimed to determine changes in the shape and volume of the infrapatellar-fat-pad between 30° and 0° of knee extension in knee osteoarthritis cases and in young, healthy individuals, and to characterize differences in patellar mobility, patellar tendon mobility, and length between the groups. [Participants and Methods] We created 3D models of the infrapatellar-fat-pad, the patellar tendon, and bones using sagittal MRI with the knee at 30° and 0°. The following four parameters were determined: (1) movement of the infrapatellar-fat-pad; (2) infrapatellar-fat-pad volume; (3) angle and surface length of the patellar tendon; and (4) patellar movement. [Results] Compared with the knee osteoarthritis group, the healthy group showed (1) reduced anterior movement of the infrapatellar-fat-pad; (2) smaller volume changes only in the infero-postero-lateral portion; and (3) no changes in the angle of the patellar tendon to the tibial plateau between 30° to 0°. [Conclusion] In conclusion, between 30° and 0°, (1) the infrapatellar-fat-pad in patients with knee osteoarthritis exhibited less anterior movement, and (2) the patellar tendon angle was diminished in patients with knee osteoarthritis compared with those of young-healthy knees.

Volume and mobility of the infrapatellar fat pad during quasi-static knee extension after manual therapy in patients with knee osteoarthritis: a randomized control trial study.

[Purpose] This study aimed to determine whether the volume and mobility of the infrapatellar fat pad (IPFP) change as a result of manual release or stretching during quasi-static knee extension in patients with knee osteoarthritis (KOA). [Participants and Methods] Fourteen patients with KOA were allocated to one of two groups: the manual release (R) and stretching (S, control) groups. They all underwent 12 treatment sessions in in a space of four weeks. We created 3D models of the IPFP, tibia, patella, and patellar tendon using sagittal MRI scans with the knee at 30° or 0°. We compared the differences in (1) the distance of anterior movement of the anterior surface of the IPFP (IPFP movement) and (2) the volume of the IPFP, between the R and S groups, using the 3D models. [Results] Neither group showed any anterior movement of the IPFP during quasi-static knee extension at pre-intervention; however, both groups showed significant anterior movement of the IPFP at post-intervention. IPFP movement decreased in the S group, meanwhile it increased in the R group at post-intervention. [Conclusion] Anterior movement of the IPFP was more increased by manual release than by stretching since the latter may have shortened the distance between the patella and tibial tuberosity at 0° and 30° flexion.

Repeatability of quantification of extrusion of the medial meniscus in knee osteoarthritis using three-dimensional models.

Objective: Meniscal damage is one of risk factors for the development of knee osteoarthritis (KOA). Medial meniscal extrusion (MME) is associated with the progression of cartilage loss in the medial compartment. The objective of this study was to determine the intra-rater repeatability of our method of three-dimensionally analyzing MME in patients with KOA. Design: Eight knees with medial KOA were examined in participants aged between fifty and eighty years old. We created three-dimensional models of the tibia and medial meniscus using a 0.4 Tesla MRI scanner and embedded a local coordinate system into the tibia. Repeatability of measurements of the MME volume and width were tested using intraclass correlation coefficient (ICC). Results: The ICC for measuring the MME volume was 0.998 [95% confidence interval, 0.992, 1.000]. Measurement error for the MME volume was 0.5-7.0%. The ICC for measuring the MME width was 0.983 [0.924, 0.996]. Measurement error for the MME width was 0.0-11.4%. There was no correlation between the MME volume and width (r = 0.565, p = 0.145). Conclusions: This study concluded that three-dimensional volume and width measurements of the MME by a single rater using MRI images had high repeatability even in the limited image quality. The result of non-significant correlation between the MME width and volume suggests that MME width measured using a low-magnet MRI scanner not considered reliable. Further studies are needed to determine the association between the MME volume and disease progression of KOA.