RESUMO
This first study of the pattern of allergen-specific IgE in Nigerian asthmatic patients in Zaria shows a significant percentage with specific IgE to Dermatophagoides pteronnyssinus, Aspergillus fumigatus, and Cynodon dactylon (Bermuda grass). Total serum IgE varied in both urban and rural asthmatics with a pattern of low and high levels in all groups.
Assuntos
Asma/imunologia , Imunoglobulina E/imunologia , Adulto , Anticorpos Anti-Idiotípicos/análise , Especificidade de Anticorpos , Asma/terapia , Dessensibilização Imunológica , Humanos , Imunoglobulina E/análise , Nigéria , Teste de RadioalergoadsorçãoRESUMO
The prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency was estimated in 318 diabetic patients using Beulter's fluorescent Spot test. A significantly (p less than 0.001) higher prevalence of G6PD deficiency was detected among diabetic patients (19.6%) as compared to controls (10.4%). The distribution of G6PD deficiency varied with age, sex, and duration of diabetes. Among diabetic men, the prevalence of deficiency was significantly higher than controls in both age groups; 40 years and below, and 41 years and above (p less than 0.005 and p less than 0.02, respectively). Among diabetic women, the significantly higher prevalence of deficiency was observed only in the young age group (p less than 0.005), whereas the difference among the older age group was not significant (p greater than 0.1). A significant increase in the prevalence of deficiency with increase in duration of diabetes was detected among men (p less than 0.05), but not in women. The results of the study suggest a positive association between G6PD deficiency and diabetes mellitus.
Assuntos
Complicações do Diabetes , Deficiência de Glucosefosfato Desidrogenase/complicações , Adulto , Estudos Transversais , Diabetes Mellitus/epidemiologia , Feminino , Deficiência de Glucosefosfato Desidrogenase/epidemiologia , Humanos , Iraque , MasculinoRESUMO
Glucose-6-phosphate dehydrogenase was tested in the blood of 305 males and 394 females, with Beutler's fluorescent spot test being used for screening. The percentage of deficiency was estimated at 12.4% for males and 8.8% for females of all ages; it was, however, highest among children and lowest among those over 50 years. The efficiency of the fluorescent screening test in detecting heterozygote females was estimated at 35% and was derived by determining gene frequencies and comparing the expected and the observed.
