RESUMO
To identify the true contribution of toxoplasmosis to fetal loss and bad obstetric history, we tested 310 women, 77.4% of whom had had single or multiple fetal loss, for evidence of infection. The study was conducted in Duhok, northern Iraq, from July 2002 till September 2003. All the women were examined for the presence of toxoplasma-specific IgM antibodies by enzyme-linked immunofluorescent assay; only 3 (0.97%) tested positive. We also tested 187 of the women by latex agglutination test; 55 tested positive. Histopathological examination was done for 9 pregnant women who tested positive by the latex agglutination test but we found no evidence of toxoplasma infection. The results indicate that the contribution of toxoplasmosis to fetal loss in our region is greatly overestimated.
Assuntos
Mortalidade Fetal , Complicações Parasitárias na Gravidez/epidemiologia , Toxoplasmose Congênita/epidemiologia , Toxoplasmose/epidemiologia , Aborto Espontâneo/parasitologia , Adolescente , Adulto , Anticorpos Antiprotozoários/sangue , Viés , Causalidade , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Imunoglobulina M/sangue , Iraque/epidemiologia , Testes de Fixação do Látex , Pessoa de Meia-Idade , Placenta/parasitologia , Gravidez , Complicações Parasitárias na Gravidez/sangue , Complicações Parasitárias na Gravidez/diagnóstico , Complicações Parasitárias na Gravidez/imunologia , Resultado da Gravidez/epidemiologia , Estudos Soroepidemiológicos , Toxoplasmose/sangue , Toxoplasmose/diagnóstico , Toxoplasmose/imunologia , Toxoplasmose Congênita/sangue , Toxoplasmose Congênita/diagnóstico , Toxoplasmose Congênita/imunologia , População Urbana/estatística & dados numéricosRESUMO
To identify the true contribution of toxoplasmosis to fetal loss and bad obstetric history, we tested 310 women, 77.4% of whom had had single or multiple fetal loss, for evidence of infection. The study was conducted in Duhok, northern Iraq, from July 2002 till September 2003. All the women were examined for the presence of toxoplasma-specific IgM antibodies by enzyme-linked immunofluorescent assay; only 3 [0.97%] tested positive. We also tested 187 of the women by latex agglutination test; 55 tested positive. Histopathological examination was done for 9 pregnant women who tested positive by the latex agglutination test but we found no evidence of toxoplasma infection. The results indicate that the contribution of toxoplasmosis to fetal loss in our region is greatly overestimated
