RESUMO
Metastases to the pituitary gland is a rare complication of systemic cancer in adults (does not practically occur in children). In 1857 L.Benjamin was the first who described a case of metastasis to the pituitary gland at autopsy of a patient with disseminated melanoma. Metastases in the pituitary gland are marked in 0,14-28,1% of all metastases to the brain in several series of autopsies. Many researchers consider that metastases in the pituitary gland are met in 1% of patients who underwent transsphenoidal surgery and 5% of autopsies.
Assuntos
Hipófise/patologia , Neoplasias Hipofisárias/patologia , Humanos , Metástase Neoplásica , Hipófise/diagnóstico por imagem , Neoplasias Hipofisárias/diagnóstico por imagem , Neoplasias Hipofisárias/secundárioRESUMO
An overview of the methods of fixation of the skull bones is presented,as well as discussion and characterization of different methods of fixation. A new system of fixation of the skull bones was used in osseous-plastic trepanation and reconstructive operations using nitinol craniofixators. Results of cranioplasty using craniofixators were analyzed in 62 patients with craniocerebral injuries and its consequences, vascular and oncological diseases of the brain. There were no complications in the postoperative period. Articles made of nitinol are very strong, elastic and have the effect of thermo-mechanical memory of the form.
Assuntos
Ligas , Fixação de Fratura/instrumentação , Traumatismos Cranianos Fechados/cirurgia , Procedimentos de Cirurgia Plástica/instrumentação , Fraturas Cranianas/cirurgia , Osso Temporal/lesões , Seguimentos , Traumatismos Cranianos Fechados/diagnóstico por imagem , Humanos , Masculino , Radiografia , Fraturas Cranianas/diagnóstico por imagem , Osso Temporal/cirurgia , Adulto JovemAssuntos
Neoplasias Encefálicas/diagnóstico , Neoplasias Encefálicas/terapia , Germinoma/diagnóstico , Germinoma/terapia , Adolescente , Animais , Biomarcadores Tumorais/análise , Neoplasias Encefálicas/patologia , Quimioterapia Adjuvante , Irradiação Craniana , Germinoma/patologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Prognóstico , Dosagem Radioterapêutica , Radioterapia AdjuvanteRESUMO
7 cases of pituitary adenomas with the pronounced signs of invasive growth, confirmed by MRI, clinical and intraoperative observations. Invasive growth of adenomas was related to neither the structure of the tumor, the degree of anaplasia, or the nature of a generated hormone.
Assuntos
Adenoma/diagnóstico , Neoplasias Hipofisárias/diagnóstico , Adenoma/metabolismo , Adenoma/patologia , Adulto , Biomarcadores/metabolismo , Feminino , Humanos , Imuno-Histoquímica , Queratinas/metabolismo , Imageamento por Ressonância Magnética , Masculino , Invasividade Neoplásica , Neoplasias Hipofisárias/metabolismo , Neoplasias Hipofisárias/patologiaRESUMO
Surgery for brain metastases is an effective treatment for most cancer patients. It involves low post-operative lethality (2.9%) and causes neurological symptoms to regress in most patients. 12-month survival occured in 48.5%, 5 years--10.8%; mean survival duration with good quality of life--11.8 months. Survival basically depended on tumor pattern, metastases to other organs, multiple foci in the brain and habitus.
