Rare non-trophoblastic vascular placental tumor: A diagnostic challenge.

Key Clinical Message: Pathologists should consider the differential diagnoses of placental chorioangioma, which encompass chorangiosis, chorangiomatosis, chorangiocarcinoma, intervillous thrombus, and placental infarct. Abstract: Chorioangiomas are rare non-trophoblastic vascular neoplasms of the placenta, occurring in approximately 1% of pregnancies. Large chorioangiomas (>4 cm) are infrequent and associated with an increased risk of pregnancy complications. There are limited reports in the literature regarding uncomplicated cases of large placental chorioangiomas.

A rare and distinct bilateral ovarian tumor: Carcinosarcoma.

Carcinosarcomas are aggressive biphasic neoplasms composed of high-grade, malignant, epithelial, and mesenchymal elements. They usually occur in the uterus and rarely involve the ovaries. Only 10% of them are bilateral. Their diagnosis relies on histological examination coupled with immunohistochemistry.

Squamous cell carcinoma arising in a mature cystic teratoma of the ovary.

Ovarian teratomas with an extensive solid component in patients aged more than 40 years should raise the suspicion of malignancy. Such specimens should be thoroughly sampled, and the patient must be followed up for a long period.