[Effect of low temperatures (-196 degrees) and of cryoprotectors on some bacterial species]. / Vliianie nizkikh temperatur (-196 gradusov) i krioprotektorov na nekotorye vidy bakterii.

The effect of low temperatures (-196 degrees C) and cryoprotectors (PEO-400 and glycerol) on the survival, morphological and functional properties was studied with Escherichia coli, Serratia marcescens and Staphylococcus aureus 209. When the cells were frozen for a short period of time in liquid nitrogen, the survival and the rate of protein synthesis decreased in the gram-negative bacteria but remained almost the same in Staphylococcus aureus. PEO-400 and glycerol manifested cryoprotecting action on all the bacteria under study at concentrations which did not harm the bacteria.

[The effects of weak magnetic fields on bacteria]. / Vliianie slabogo magnitnogo polia na nekotorye vidy bakterii

A stationary device was constructed for conducting experiments in a weak magnetic field. A ferromagnetic screen was used to produce in the working volume a magnetic-field of 26 nT. The effect of a weak magnetic field on the following bacteria was studied: E. coli communior, B. prodigiosum, Staphylococcus aureus 209, and Bac. anthracoides. Cultivation of the bacteria in these conditions for a long time resulted in changes of their tinctorial, morphological, cultural, and biochemical properties.

[Study of the pharmacokinetics of phosphemide in rats with the use of physico-chemical methods]. / Izuchenie farmakokinetiki fosfemida u krys s pomoshch'iu fiziko-khimicheskikh metodov

A study on the passage of phosphemide with urine and distribution of the drug over the organs and tissues of intact (without fumour) rats and those with sarcoma-45 showed the bulk of unchanged drug to be excreted together with the urine during the first 3-4 hours following its intravenous and intraperitoneal administration. In rats with sarcoma-45 phosphamide is passed with urine in a somewhat greater amount than in the intact animals. With intravenous application the rate of the drug elimination in intact rats and in the ones with carcoma-45 is virtually the same, being somewhat lower with intraperitoneal injection of phosphemide.