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Clin Neurol Neurosurg ; 110(3): 302-4, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18160211

RESUMO

Brainstem tuberculoma is an uncommon entity especially in the immunocompetent adult. The authors describe the case of a 32-year-old immunocompetent woman with no systemic signs or symptoms of tuberculosis, presenting with sudden-onset hemiparesis and diplopia. MRI of brain revealed an enhancing lesion in the midbrain and thalamus. Cerebrospinal fluid examination was normal. Chest imaging was consistent with miliary tuberculosis; however initial expectorated sputum was culture negative. Bronchosopy sputum culture was positive for Mycobacterium tuberculosis. Her PPD was negative. Patient became asymptomatic with treatment for tuberculosis and follow-up MRI showed complete resolution of the lesion a year later. We conclude that a high index of suspicion is essential to make an early diagnosis of intracranial tuberculoma, since often, traditional TB tests like PPD and sputum examinations can be negative.


Assuntos
Tronco Encefálico/patologia , Imunocompetência , Tuberculoma Intracraniano/patologia , Adulto , Antituberculosos/uso terapêutico , Broncoscopia , Feminino , Humanos , Imageamento por Ressonância Magnética , Escarro/microbiologia , Tegmento Mesencefálico/patologia , Tálamo/patologia , Teste Tuberculínico , Tuberculoma Intracraniano/tratamento farmacológico , Tuberculose Miliar/complicações , Tuberculose Miliar/patologia
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