RESUMO
Stevens-Johnson syndrome (SJS) is a severe cutaneous reaction seen rarely in clinical practice. Most often, it occurs as an adverse reaction to certain drugs. When it affects children at a very young age, arrested tooth root development may also be seen. We present a case of a 13 year old boy who suffered from SJ syndrome at the age of 7 years. Incomplete root development was observed in all teeth, as demonstrated by panaromic radiography. Clinical features of this condition and its management are further discussed. We aim to emphasise on the need for dental practitioners to be aware of the potential dental complications of SJS and enable them to recognise and manage the condition at the earliest so as to avoid any undesirable sequelae. Key words:Adverse drug reaction, amoxycillin, arrested root development, Stevens-Johnson syndrome.
RESUMO
Mast cells (MCs) are resident cells of several types of tissues and contain many granules rich in histamine and heparin. They are distributed preferentially about the micro-vascular endothelial cells in the oral mucosa. These cells play a key role in the inflammatory process and thus their number has been found to be altered in various oral pathological conditions such as oral pyogenic granuloma, oral lichen planus, leukoplakia, oral squamous cell carcinoma, periapical cysts etc. The present review article is aimed to describe the alteration in the number of MCs along with their probable roles in these pathological conditions.
RESUMO
INTRODUCTION: The study was designed as a randomized controlled trial to evaluate the effect of the apical preparation size in relation to the first apical binding file (FABF) on the outcome of primary endodontic treatment in mandibular first molars. METHODS: One hundred sixty-seven patients met the inclusion criteria. They were randomly allocated to 5 different endodontic treatment groups (ie, A, B, C, D, and E) in which canals were enlarged to 2, 3, 4, 5, and 6 sizes larger than the FABF, respectively. One hundred twenty-nine patients were evaluated at the 12-month follow-up. The primary outcome measure was the change in periapical radiolucency as assessed by periapical index (PAI) scores. The clinical finding constituted the secondary outcome measure. RESULTS: A statistically significant reduction in PAI scores was observed in all groups (P < .001). The proportion of successfully healed cases increased with an increase in the apical preparation size with 48%, 71.43%, 80%, 84.61%, and 92% successful healing observed in groups A to E, respectively. However, statistical analysis revealed that only group A showed significantly less improvement than other groups (P < .05). No significant difference was observed between the rest of the groups. Regression analysis revealed a significant and positive association between the master apical preparation size and an improvement in PAI scores (ß = 0.037, P = .001). CONCLUSIONS: The enlargement of the canal to 3 sizes larger than the FABF is adequate, and further enlargement does not provide any additional benefit during endodontic treatment.
