1.
Nucleosides Nucleotides Nucleic Acids
; 22(5-8): 739-42, 2003.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14565267
RESUMO
A synthetic approach towards 1'-C-branched N,O-nucleosides is reported, based on 1,3-dipolar cycloaddition of ethoxycarbonylnitrone. The asymmetric version of the process exploits the presence of a chiral auxiliary at the carbon atom of nitrone and leads to beta-D and beta-L nucleosides in good yields.