[Iodine deficiency in the prenatal period may form learning ability deficiency in the postnatal period].

The present study analysis the changes in learning ability of the progeny of rats suffered from iodine deficiency. Reduction of serum thyroxin in the mothers' blood during three months before mating and whole period of gestation to an average level of 4,7+/-0,6 ng/ml, significantly worsened the learning ability in progeny, and the reduction to 1,1+/-0,4 ng/ml - completely deprived progeny's learning ability. Passage of the maze for these animals was purely probabilistic in nature without any signs of learning We can conclude that the diet with very low iodine content results in a low level of thyroxin in maternal serum and neurological deficiency in progeny manifested by learning disability during maze testing. Addition of the iodine to the diet prevents development of mentioned neurological deficiency.

[Analgetic property of nonspecific thalamic nuclei].

Neruronal activity evoked by pain impulsation in the specific thalamic nuclei and sensorimotor cortex has been recorded in cat. The following data were obtained. Evoked nociceptive neuronal activity was inhibited by stimulation of the nonspecific thalamic nuclei. An antinociceptive impact of the nonspecific thalamic nuclei on the specific thalamic units was fulfilled by both direct and thalamo-cortico-thalamic pathways. Stimulation of the antinociceptive regions of the nonspecific thalamic nuclei abolished evoked nociceptive activity of the cortical units, elicited by both peripheral noxious stimulus and stimulation of the ventro-postero-medial thalamic nuclei. This indicates that the nonspecific thalamic nuclei inhibit the cortical activity on the thalamic, as well as, on the cortical level.

[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord]. / Vliianie klofelina na impul'snuiu aktivnost' neironov srednego mozga i zadnego roga spinnogo mozga.

Clophelin (1-5 mg/kg) suppresses spinal dorsal horn neuronal nociceptive responses but does not change their touch stimuli reactions in unanesthetized curarized cats. This effect is steady to naloxone (1 mg/kg), yohimbine (5 mg/kg) and removal by prazosin (1 mg/kg). Clophelin depresses nociceptive responses of the central gray matter neurones which generalized pain impulses in the supraspinal structures.

[Effect of electroacupuncture on the activity of neurons in the central gray matter of the midbrain]. / Vliianie élektroakupunktury na aktivnost' neironov tsentral'nogo serogo veshchestva srednego mozga.

The effect of electroacupuncture in locally-segment and general analgetic points on background impulse activity of central gray substance neurons and their activity caused by nociceptive stimulation of the dental pulp, infraorbital nerve and forearm skin surface was studied in acute experiments on cats. It has been established that general analgetic points are better represented in the central gray substance, as compared to locally-segment points. Different degree involvement of central gray substance in the realization of acupuncture analgetic effect in different points is postulated. The role of dorsal and ventral compartments of the central gray substance in acupunctural analgesia is discussed.