Fertilidad posterior a la septoplastia histeroscópica de consultorio. Una propuesta de clasificación del septo uterino / Fertility after hysteroscopic septoplasty surgery. A proposed classification for the septum uterine

Resumen ANTECEDENTES: Las malformaciones müllerianas son anomalías del desarrollo de los genitales internos femeninos. La incidencia mundial es de 0.16 a 10%. La más común es el útero septado, consecuencia de una falla en la reabsorción del tabique útero-vaginal. OBJETIVO: Evaluar, en la población estudiada, la repercusión de la septoplastia histeroscópica en la fertilidad de mujeres con útero septado. MATERIALES Y MÉTODOS: Estudio abierto, observacional, retrospectivo y transversal de pacientes de la Clínica de Histeroscopia del Hospital General Dr. Manuel Gea González, con diagnóstico de infertilidad establecido con auxilio de la técnica de acceso por vaginoscopia, según Betocchi, siguiendo el concepto de "ver y tratar". RESULTADOS: Se revisaron 508 expedientes y de estos se seleccionaron 313 de pacientes a quienes se practicó histeroscopia diagnóstica de las que 32 resultaron con septo uterino. Se efectuaron 27 septoplastias histeroscópicas en consultorio y 5 programadas en quirófano. En 27 (84.3%) se logró el embarazo y de éstos 5 mediante fertilización asistida; hubo 8 nacimientos prematuros y 17 a término y 2 abortos diferidos. CONCLUSIÓN: Hoy día la septoplastia histeroscópica es la alternativa de tratamiento del septo uterino debido a su facilidad de realización en el consultorio por personal adiestrado, baja morbilidad, menores costos, rápida recuperación y excelente resultado reproductivo. Se propone una clasificación de acuerdo con el componente del septo.

Abstract BACKGROUND: Müllerian malformations are defined as anomalies development of female internal genitalia. Its incidence worldwide is 0.16% to 10%. The most common of these is the septate uterus which is due to a failure in the reabsorption of uterovaginal septum. OBJECTIVE: To evaluate the impact on fertility hysteroscopic septoplasty in women with uterine septum. MATERIAL AND METHODS: This is an open, observational, retrospective and cross-sectional study. 508 cases of which 313 patients underwent diagnostic office hysteroscopy hysteroscopy clinic were reviewed Hospital General Dr. Manuel Gea González, diagnosed with infertility, you access using the technique vaginoscopic according Betocchi, following the concept of" see and treat ", proceed to perform septoplasty with bipolar energy at that moment. RESULTS: 32 patients were diagnosed with uterine septum. 27 hysteroscopic septoplasty were performed in office and five scheduled in the operating room. 27 of them achieving pregnancy (84.38%) spontaneously regarding perinatal outcomes of those 27 patients who achieved pregnancy 2 had missed abortion, premature 8 were 17 were concluded; 5 required assisted fertilization. CONCLUSION: The hysteroscopic septoplasty is now recommended for the treatment of uterine septum due to ease of performance by trained personnel, low morbidity, the feasibility of its implementation in practice, reduced cost, speedy recovery of patients and excellent reproductive outcome alternative. Classification according to the component of the septum is proposed.

[Initial experience with a minidose of methotrexate in the management of unruptured ectopic pregnancy]. / Experiencia inicial con un esquema de minidosis única de metotrexate para el manejo de embarazo ectópico no roto.

Methotrexate has been used in the conservative management of ectopic pregnancy with good results. Due to its great afinity for the trophoblast it was decided to try unique doses of 50 mg i.m. independently of the body surface. Fifteen patients were studied with ectopic pregnancy by ultrasound and hCG in series that didn't require confirmatory laparoscopy. The ectopic pregnancies broken and/or decompensated were discarded. Average gestational age was 6.1 weeks; the maximal dimention of the sacs was 36.8 mm average; the values for hCG average were 6440 mU/ml and the maximal time of negativization was 52 days. One patient required laparoscopy and salpingostomy, lineal, for inminent rupture 24 hour after methotrexate, the other 14 presented with complete remission. There were no colateral effects. From the 15 patients, in 6 tubal permeability was confirmed by laparoscopy or HSG, being positive in 6 patients, it has not been evaluated, two patients with resolved pregnancy, and other on course (two of them with one salpinx). The proposed management seems to be useful in ectopic pregnancy with success, equivalent to surgical management, and other programs of medical management, with out side effects and with greater easiness of administration.

[Catheterization of the tubal ostium using hysteroscopy under laparoscopic guidance]. / Cateterización del ostium tubario bajo guía histeroscópica con control laparoscópico.

It is considered that one out of five couples present a transitory problem of infertility during their reproductive life and the most frequent cause is the tubarian pathology; from these, the proximal obstruction occupies between 25 and 30% of the cases. Unfortunatelly, the conventional method use to study tubarian patency such as histerosalpingography or the direct observation by laparoscopy and selective chromotubation, frequently do not allow to differentiate between an insufficient filling of the tubes, tubarian spasm or a true mechanical obstruction. There are certain selective tubarian cannulation techniques, for example, the catheterism with hysteroscopic guidance which is extremely usefull in the diagnosis of tubarian patency or in the confirmation of partial or total proximal tubal disease. The procedure permits to diagnosticate precisely the tubarian obstruction and also if it is due to the presence of a true pathology or simply functional, or secondary to a tubarian spasm; besides it also works as a therapeutic procedure since in the first case permits the lysis of laxe adherencies and the removal of the amorfus material that obstructs the tube and permits the catheterization. The present study determines the utility of catheterization of the tubarian ostium by hysteroscopy with laparoscopic control using the Novy (Cook, Ob/ Gyn) catheter in patients with infertility problems due to proximal obstruction of one or both of the fallopian tubes, to confirm or discard the presence of a pathological obstruction. The results are evaluated in terms of tubarian permeability and the pregnancy rate after the procedure.

[Laparoscopy and hysteroscopy in Müllerian duct malformations: usefulness and reproductive results]. / Laparoscopia e histeroscopia en malformaciones müllerianas: utilidad y resultados reproductivos.

Determine the type and the possibility of corrective surgery, reproductive results of infertility patients with Müllerian malformations. The clinic and the laparoscopic and hysteroscopic evaluation were performed to 40 patients with Müllerian anomalies and infertility history analyzing the reproductive results. The uterine septum was present in 23/40 patients (57.5%), bicornual uterus in 6/40 (15%), didelfus uterus 5/40 (12.5%), arcuate uterus 4/40 (10%), unicorn uterus 2/40 (5%). After septum resection we had 13 pregnancies (56.5%). 2 abortions, 4 already delivered and 7 continue normal evolution with on twin case. Strassman metroplasty by laparotomy was performed in 4 cases of bicornual uterus achieving pregnancy in two cases. In one didelfus uterus, a salpingoclasy of the smaller horn was done as an alternative. Of the arcuated uterus, the small septum was removed. Of the unicorn uterus, one pregnancy was lost in the first trimester and the other one reach the term date. Our data show that the endoscopic procedures can perform the correct diagnosis of the Müllerian anomalies and of course the best surgical treatment improving the fertility rates.

[Tubo-peritoneal factor. Endometriosis]. / Factor tuboperitoneal. Endometriosis.

Fifty cases of tuboperitoneal endometriosis with sterility, are reviewed. Laparoscopy was done in all the patients to confirm disease, and its severity was classified to AFS; 18 cases were of minimal endometriosis; 8 slight; 12 moderate; and 12 severe. The endometriotic profile in our environment is described and compared with which has been described in progresist countries; 32% of pregnancy at term, was obtained. The possible mechanisms producing sterility, are mentioned.

[Diagnostic and therapeutic management and results of the neuroendocrine factor in sterility]. / Conducta diagnóstica terapéutica y resultados del factor neuroendocrino en esterilidad.

One hundred and fifty patients with neuroendocrine alteration, mainly anovulation, proven by basal temperature and endometrial biopsy, were studied. Clinical history and basic examinations for sterility, were carried out. The neuroendocrine factor, alone or associated, was found in 35% of the patients studied for sterility. Primary sterility was 59.3% of the cases. The vagino-cervico-spermatic factor was the most frequent one associated to the neuroendocrine one (28%). Ovulation was induced in 62.6% of the cases. Pregnancy was achieved in 65 patients (43.3%; 80% reached term, and 20% were abortions.