RESUMO
BACKGROUND: Manual segmentation of the Foveal Avascular Zone (FAZ) has a high level of variability. Research into retinas needs coherent segmentation sets with low variability. METHODS: Retinal optical coherence tomography angiography (OCTA) images from type-1 diabetes mellitus (DM1), type-2 diabetes mellitus (DM2) and healthy patients were included. Superficial (SCP) and deep (DCP) capillary plexus FAZs were manually segmented by different observers. After comparing the results, a new criterion was established to reduce variability in the segmentations. The FAZ area and acircularity were also studied. RESULTS: The new segmentation criterion produces smaller areas (closer to the real FAZ) with lower variability than the different criteria of the explorers in both plexuses for the three groups. This was particularly noticeable for the DM2 group with damaged retinas. The acircularity values were also slightly reduced with the final criterion in all groups. The FAZ areas with lower values showed slightly higher acircularity values. We also have a consistent and coherent set of segmentations with which to continue our research. CONCLUSIONS: Manual segmentations of FAZ are generally carried out with little attention to the consistency of the measurements. A novel criterion for segmenting the FAZ allows segmentations made by different observers to be more similar.
RESUMO
Near-infrared supercontinuum generation by using silica-based highly-nonlinear fiber placed inside of the ring-cavity of an erbium-doped fiber laser pulsed by mode-locking is experimentally demonstrated. Only one erbium-doped fiber amplifier is employed to generate supercontinuum with a spectral width as long as 830 nm (from 1205 to 2035 nm) and a spectral power higher than -30 dBm/nm. To generate supercontinuum, it is not necessary a second amplifier to raise the power of the laser pulses coupled into the nonlinear fiber. Moreover, all the devices employed are commercial and available at any photonics laboratory. To the best of our knowledge, this is the first demonstration of this kind of device by pumping the nonlinear fiber in the third window of communications.
