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Herz ; 45(8): 719-725, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33216154

RESUMO

BACKGROUND: In late 2019, a cohort of patients presenting with pneumonia of unclear etiology in Wuhan, China, heralded the outbreak of coronavirus disease 19 (COVID-19). Previous severe acute respiratory syndrome (SARS) beta-coronavirus infections have been associated with tachyarrhythmias and signs and symptoms of heart failure. The emergence of SARS coronavirus 2 (SARS-CoV-2), which causes COVID-19, has rapidly developed into a pandemic, and a large number of infected patients have been reported to have underlying cardiovascular disease. OBJECTIVE: Since there are only scant published data regarding cardiovascular burden in the wake of viral epidemics, this study aimed to evaluate cardiac involvement in COVID-19. MATERIAL AND METHODS: This prospective cohort study included 40 adult inpatients at two centers in Germany. Adult patients diagnosed with COVID-19 in accordance with World Health Organization (WHO) interim guidance were included in the study, which focused on the potential cardiac involvement of SARS-CoV­2. It was based on laboratory parameters as well as electro- and echocardiographic values to determine the impact of SARS-CoV­2 virus on heart tissues. RESULTS: The conducted investigations confirmed the relationship between the presence of acute cardiac injury and COVID-19. CONCLUSION: Myocardial injury and impaired myocardial function due to COVID-19 are common; however, no correlation was established between cardiac laboratory or echocardiographic values and mortality. Cardiovascular monitoring upon COVID-19 infection is crucial to determine the burden of cardiac involvement.


Assuntos
Infecções por Coronavirus , Coronavirus , Miocárdio , Pandemias , Pneumonia Viral , Adulto , Betacoronavirus , COVID-19 , China/epidemiologia , Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/epidemiologia , Alemanha/epidemiologia , Humanos , Miocárdio/patologia , Estudos Prospectivos , SARS-CoV-2
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