Social perception drives eye-movement related brain activity: Evidence from pro- and anti-saccades to faces.

Social stimuli such as faces attract and retain attention to a greater extent than other objects. Using fMRI, we investigated how the activity of oculomotor and visual brain regions is modulated when participants look towards or away from visual stimuli belonging to different categories (faces and cars). We identified a region within the superior frontal sulcus showing greater difference between anti- and pro-saccades to faces than to cars, and thereby supporting inhibitory control in a social context. In contrast, ventral occipito-temporal regions and the amygdala, which are associated with face perception, showed higher activity for pro-saccades than anti-saccades for faces, but the reverse for cars, suggesting that contextual, top-down mechanisms modulate the functional specialisation of areas involved in perception. In addition, during saccades in the presence of faces, we found increased functional connectivity between the frontal eye-fields and other cortical and subcortical oculomotor structures, namely the inferior frontal eye field, the posterior parietal cortex and the basal ganglia, possibly reflecting the higher demand put on the oculomotor system to inhibit responses to socially salient stimuli. For the first time, these data highlight neural bases for the different orienting responses towards or away from faces as compared to other objects.

Measuring workload with electrodermal activity during common braking actions.

How to assess mental load remains a recurrent question. We aimed to explore whether slight differences in real-world driving task demands could be discriminated by electrodermal response (EDR). A sample of 33 participants was observed under five conditions: controlled braking from 50 to 30 km/h, 80 to 50 km/h, 50 to 0 km/h, 80 to 0 km/h, and a single unexpected emergency braking event from 80 to 0 km/h. The likelihood of EDR and, whenever present, its duration were both correlated with workload as represented by the deceleration demand. A higher base travel speed and the unexpected demand of the emergency braking situation impacted EDR, thus attesting higher workload level. EDR explains why stopping the vehicle from 50 km/h and slowing down from 80 to 50 km/h was of similar strain. The results further demonstrate that EDR measures can be successfully employed to discriminate multiple levels of workload. PRACTITIONER SUMMARY: Common braking elicited different loads as revealed by electrodermal response (EDR) with sensitivity to deceleration of - 0.2 g. Even the slightest braking elicited a strain measurable with EDR. Accordingly, EDR may objectively assess the resulting strain during driving, with enhanced reliability if associated with other variables, e.g. cardiac activity.

Delayed contrast enhancement magnetic resonance imaging in congenital aortic stenosis.

We report a case of a 12-year-old boy with severe congenital aortic stenosis in whom magnetic resonance imaging (MRI) with delayed contrast enhancement demonstrated extensive subendocardial hyperenhancement within the left ventricle. The hyperenhancement was confirmed to be subendocardial infarct and fibrosis by histopathology. This case supports the utility of MRI with delayed contrast enhancement in evaluating myocardial viability in patients with congenital heart disease.