[ADRENERGIC AND CHOLINERGIC INNERVATION OF THE PHARYNGEAL TONSILS IN CHILDREN WITH CHRONIC ADENOIDITIS].

Adrenergic and cholinergic innervation of the pharyngeal tonsil was studied in 50 children aged 4 to 14 years with chronic adenoiditis. that was removed during the operation from. The children were divided into 3 groups. The 1st group included children with decreased tone of the autonomic nervous system (ANS) and autonomic hyperreactivity, the 2nd group ­ children with increased ANS tone and low autonomic reactivity, the 3rd group ­ children with optimal autonomic tone and normal reactivity. The state of the nervous structures in the region of adenoid overgrowths was studied by histochemical methods, demonstrating adren- and cholinergic nerve fibers in the same section (incubation in glyoxylic acid and Karnovsky­Roots method). Adrenergic nerve fibers with many varicosities were found mainly in perivasal plexuses, from which the branches passed subepithelially between the nodules, and the terminals ofthin fibers penetrated the lymphoid nodules. The assessment of the functional activity of adrenergic nerve fibers demonstrated that in the 1st group the average luminescence intensity in varicose extensions and intervaricose areas was equal to 22.7±2.5 and 37,2±3.5 conventional units (c.u.), respectively, in the 2nd group it was equal to 57.3±1,4 and 15.5±4.3 c.u., while in the 3rd group ­ to 34,3±2,2 and 30.1±3.8 c.u. It was found that cholinergic nerve fibers were located similarly to adrenergic fibers, but appeared thicker and had larger varicosities. The activity of cholinergic nerve structures could be evaluated by the staining intensity (from light yellow to dark brown) and by the number of varicose extensions in a certain fiber. Similar to adrenergic fibers, cholinergic nerve fibers often passed from perivascular plexuses and innervated the lymphoid tissue.

[Genotype-specific changes of certain functional indicators of immunocompetent cells in male laboratory mice under conditions of pheromone stress]. / Genotipspetsificheskie izmeneniia nekotorykh funktsional'nykh pokazatelei immunokompetentnykh kletok u samtsov laboratornykh myshei v usloviiakh fermonal'nogo stressa.

Mature laboratory male mice CBA, C57BL/6, BALB/c, and hybrids CBAB6F1 were exposed for 2 or 24 h to vapors of 2,5-dimethylpyrazine (DMP), which is a pheromone of the house mouse. This caused changes in the content of noradrenaline within the nerve fibers of both nasal mucosa and vascular testis tunic and an inhibition of leukocyte migration in the peripheral blood. Intrastrain distinctions were also revealed in the level of spontaneous leukocyte migration and intensity of the response to the DMP. The mechanisms underlying these effects and their possible adaptive significance are discussed.

[Adrenergic innervation of nasal polyps and pharyngeal tonsil in children]. / Adrenergicheskaia innervatsiia nosovykh polipov i glotochnoi mindaliny u detei.

Vegetative nervous structures in adenoids and nasal polyps were studied histochemically. Functional parameters of the vegetative nervous system were evaluated in children with hyperplasia of the pharyngeal tonsil. Polyps are shown to have adrenergic nervous structures. 80% of tonsillar hyperplasia children exhibited vegetative dystonia. Adrenergic innervation of adenoids removed surgically is described.