Aspects of gastrointestina; immunology and nutrition in human immunodeficiency virus-1 infection in Brazil

Mucosal surfaces have a fundamental participation in many aspects of the human immunodeficiency virus (HIV) infection pathogenesis. In Brazilian HIV-1 infected subjects, loss of weight and appetite are among the most debilitating symptoms. In this review we describe a defined mucosal immunogen that has profound but transient effects on HIV viral load, and we suggest that gut associated lymphoid tissue under constant immunostimulation is likely to provide a major contribution to the total levels of HIV. We also show that hypermetabolism appears to play a role in the wasting process in Brazilian patients coinfected with HIV and tuberculosis

Paracoccidioidomicose disseminada aguda com derrame pleural: relato de um caso / Acute disseminated paracoccidiodomycosis with acute pleural effusion: a case report

Apresenta-se um caso de paracoccidioidomicose disseminada aguda em indivíduo de 30 anos do sexo masculino, no qual constatou-se extenso derrame pleural ocupando o hemitórax esquerdo. O diagnóstico foi estabelecido por biópsia ganglionar. O fungo foi visualizado na biópsia pleural. Discute-se a patogenia do derrame pleural na micose de Lutz e enfatiza-se o diagnóstico diferencial com doenças hematológicas e tuberculose