[The relationship of population morbidity to specific industrial wastes]. / Zavisimost' zabolevaemosti naseleniia ot spetsificheskikh promyshlennykh vybrosov.

The present-day ecological crisis progressively deteriorates the population's health and demographic indices. Since 1990 primary morbidity has shown a 50.2% increase in the town of Samara. There has been a rise in the incidence of diseases, primarily those of the blood, digestive, respiratory, and other systems. A correlation analysis revealed that there was an association of morbidity with the environmental content of specific industrial chemical pollutants. The incidence of respiratory diseases is related to the concentrations of CO, NO2 and SO2 in the ambient air.

[Chronic fatigue syndrome:objective criteria of metabolic defects]. / Sindrom khronicheskogo utomleniia: ob"ektivnye kriterii metabolicheskikh narushenii.

Multi-level system of defense mechanisms is studied in 206 normal subjects living in an ecologically unfavorable region and working at chemical plants. Control group consisted of 24 subjects living in en ecologically safe region. The content of total protein and albumin and its effective and binding capacity were decreased, while the content of medium molecular weight peptides increased in the blood of subjects exposed to technogenic environmental pollution. The detected shifts are regarded as a mechanism of development of chronic fatigue syndrome.

[Biologically active additive from milk thistle in the solution of public health problems]. / Biologicheski aktivnaia dobavka iz rastoropshi v reshenii problem ozdorovleniia naseleniia.

Influence of bioactive additions from natural vegetable raw materials--silybum marianum--in the content of bread products on health and metabolism was studied. It is shown bread products with silybum marianum to be effective medicine with general restorative influence, increasing internal protection resources, capacity for work and vital activity.

[Features of metabolism of the human myocardium during alcoholic intoxication]. / Osobennosti metabolizma miokarda cheloveka pri alkogol'noi intoksikatsii.

Systems of alcohol oxidation, malate-aspartate shunt, content of total and alpha-cholesterols in heart muscle and blood as well as morphometry of aorta were studied. The tissues investigated were obtained post mortem in lethal traumatic injury accompanied by increased content of ethanol in blood. The potentiating effect of alcoholization on atherogenesis was not found.

[Structure-activity features of malate dehydrogenase from human myocardium in atherosclerosis]. / Strukturno-funktsional'nye osobennosti malatdegidrogenazy iz miokarda cheloveka pri ateroskleroze.

A homogeneous preparation of malate dehydrogenase was obtained from human myocardium, the enzyme structure-functional properties were studied. Alterations in structure characteristics of the enzyme, increase in its hydrophobic moiety, decrease of the enzyme activity were observed during impairments in atherosclerosis. The alterations of the enzyme properties appear to be involved in deterioration of energy metabolism as well as they are related to activation of liposynthesis in atherosclerosis.