Descripción de pacientes con displasia del desarrollo de cadera en Hospital Clínico Herminda Martin, Chillán, entre los años 2020-2021 / Description of patients with developmental dysplasia of the hip at the Hospital Clínico Herminda Martin, Chillán, between the years 2020-2021

Introducción: La displasia del desarrollo de la cadera (DDC), una patología multifactorial más prevalente en el sexo femenino, afecta a lactantes, y el diagnóstico y tratamiento oportuno permiten evitar consecuencias posteriores, morbimortalidad significativa y una carga en salud importante. Objetivo: Conocer la realidad local en relación con el diagnóstico y tratamiento de la DDC, describiendo demográficamente a los pacientes evaluados por médicos especialistas, específicamente traumatólogos infantiles del Hospital Clínico Herminda Martin (HCHM) en Chillán. Materiales y métodos: Se llevó a cabo un estudio descriptivo transversal de una cohorte de pacientes evaluados mediante radiografías en el HCHM por sospecha de DDC, entre junio de 2020 y julio de 2021. Se recopilaron variables como sexo, tipo de compromiso del desarrollo de la cadera y tratamiento utilizado. Resultados: De 146 pacientes evaluados, el 83.6% correspondían al sexo femenino, mientras que el 16.4% eran del sexo masculino. En cuanto a los tratamientos ortopédicos, el 82.7% fueron mujeres y el 17.2% hombres, siendo las correas de Pavlik el tratamiento más utilizado. Solo 7 pacientes requirieron tratamiento quirúrgico. Discusión: Los resultados obtenidos se respaldan en la evidencia internacional, reflejando realidades similares a la situación local. La relevancia de este estudio radica en la falta de una base de datos nacional o local actualizada sobre la patología, sumado a la ventaja de informar acerca de los tratamientos disponibles y la adherencia a ellos. Esto permite reflejar el comportamiento de la población local durante los años 2020-2021. Las limitaciones incluyen el seguimiento, debido a restricciones por la pandemia y la falta de datos previos.

Introduction: Developmental dysplasia of the hip (DDH), a multifactorial pathology more prevalent in females, affects infants, where timely diagnosis and treatment avoid subsequent consequences, significant morbidity, and mortality, as well as the health burden it generates. Objective: To understand the local reality regarding the diagnosis and treatment of DDH by describing the demographic characteristics of patients evaluated by medical specialists, specifically child traumatologists from the Hospital Clínico Herminda Martin (HCHM) in Chillán. Materials and Methods: A cross-sectional descriptive study was conducted on a cohort of patients evaluated through radiographs at HCHM due to suspected DDH between June 2020 and July 2021. Variables collected included sex, type of hip development compromise, and treatment used. Results: Out of 146 patients, 83.6% were female and 16.4% were male. In terms of orthopedic treatments, 82.7% were females, and 17.2% were males, with Pavlik straps being the most used orthopedic treatment. Only 7 patients underwent surgical treatment. Discussion: The obtained results align with international evidence, reflecting realities similar to the local situation. The study's significance lies in the absence of an updated national or local database on the pathology. Additionally, it provides insights into available treatments and patient adherence, offering a snapshot of the local population's behavior during 2020-2021. Limitations include patient follow-up challenges due to pandemic restrictions and the lack of pre-existing data.

Genomic Loads and Genotypes of Respiratory Syncytial Virus: Viral Factors during Lower Respiratory Tract Infection in Chilean Hospitalized Infants.

The clinical impact of viral factors (types and viral loads) during respiratory syncytial virus (RSV) infection is still controversial, especially regarding newly described genotypes. In this study, infants with RSV bronchiolitis were recruited to describe the association of these viral factors with severity of infection. RSV antigenic types, genotypes, and viral loads were determined from hospitalized patients at Hospital Roberto del Río, Santiago, Chile. Cases were characterized by demographic and clinical information, including days of lower respiratory symptoms and severity. A total of 86 patients were included: 49 moderate and 37 severe cases. During 2013, RSV-A was dominant (86%). RSV-B predominated in 2014 (92%). Phylogenetic analyses revealed circulation of GA2, Buenos Aires (BA), and Ontario (ON) genotypes. No association was observed between severity of infection and RSV group (p = 0.69) or genotype (p = 0.87). After a clinical categorization of duration of illness, higher RSV genomic loads were detected in infants evaluated earlier in their disease (p < 0.001) and also in infants evaluated later, but coursing a more severe infection (p = 0.04). Although types and genotypes did not associate with severity in our children, higher RSV genomic loads and delayed viral clearance in severe patients define a group that might benefit from new antiviral therapies.