[Increased resistance to hypoxia under the effect of the mixture of herbs from the Altai].

We investigated the antihypoxic effect of herb mixture <> from the Altai in an experiment with rats. This mixture of herbs contains bioflavonoids. Also, it has antioxidant, anti-inflammatory, antispasmodic, angioprotective and antiplatelet properties. The animals received decoction of herbs into the stomach through a tube. Courses lasted 3, 7, 14 and 21 days. Resistance to acute hypobaric hypoxia evaluated by time of animal life in modeling rise to a height of 11,500 meters above sea level. In result, a significant antihypoxic effect was observed in rats treated with decoction of herbs for 21 days. Shorter courses of treatment were not effective.

[The chemico-pharmacological patterns in the action of plants from the family of Pyrolaceae]. / Khimiko-farmakologicheskie zakonomernosti v deistvii semeistva grushankovykh.

The effect of leaf decoctions of three plants of the Pyrolaceae family, namely, umbrella wintergreen, one-side ortilia, and round-leaf Pyrola was studied in rat experiments. All plants under study were found to contain approximately equal amounts of tannins and arbutin glycoside. Their concentration was comparable though rather lower than in common bearberry, a well-known plant with diuretic and antiseptic activity. When given for a long time, all Pyrolaceae increased urination and sodium excretion. Besides, their decoctions caused an antimicrobial effect. Only round-leaf Pyrola weakened the development of experimental inflammation. Its anti-inflammatory effect was probably due the presence of flavonoids the content of which in Pyrola was maximum.