A prospective study of factors affecting recovery from musculoskeletal injuries.

PURPOSE: Research suggests the importance of psychosocial factors in recovery from musculoskeletal injuries. The objective of this study was to identify predictors of recovery among U.S. Marines who had musculoskeletal injuries of the back, knee, or shoulder. METHODS: A sample of 134 participants was assessed at baseline and followed for 1 year to determine outcome information. RESULTS: The strongest predictor of injury recovery at the 1-year follow-up was recovery expectations. In a multivariate logistic model with key demographic and psychosocial factors controlled, individuals who had high recovery expectations at baseline were over five times as likely to be recovered at follow-up as individuals who had low expectations (OR = 5.18, p\.01). CONCLUSIONS: This finding is consistent with a large body of research that has linked recovery expectations with better recovery outcomes in patients with musculoskeletal injuries as well as with research linking recovery expectations with better outcomes across a wide range of medical conditions.Applied to military populations, interventions designed to modify recovery expectations may have the potential to improve rates of return to duty and to reduce rates of disability discharge.

Behavioral predictors of acute stress symptoms during intense military training.

A better understanding of factors influencing human responses to acute stress is needed to enhance prevention and treatment of stress-related disorders. In the current study, the authors examined predictors of acute stress symptoms during intense military training in 35 men. In univariate and multivariate models, perceived stress, passive coping, and emotion-focused coping during daily living predicted acute stress symptoms in response to realistic survival training, whereas active coping and problem-focused coping did not. Baseline stress levels and coping styles, both of which may be modifiable, appear to play a fundamental role in the human response to acute uncontrollable stress. Additional research is needed to better elucidate the relative and interactive contributions of behavioral predictors of acute stress.

Absolute serum hormone levels predict the magnitude of change in anterior knee laxity across the menstrual cycle.

This study aimed to determine whether absolute sex hormone concentrations predict the magnitude of knee joint laxity changes across the menstrual cycle. Twenty-two females (18-30 years, body mass index

Relationship between sex hormones and anterior knee laxity across the menstrual cycle.

PURPOSE: To comprehensively quantify through daily, serial measures changes in knee laxity as a function of changing sex-hormone levels across one complete menstrual cycle. METHODS: Twenty-five females, 18 - 30 yr, body mass index < or = 30, who reported normal menstrual cycles (28-32 d) over the past 6 months participated. Participants were tested daily across one complete menstrual cycle; 5-7 cc of venous blood were withdrawn to assay serum levels of estradiol, progesterone, and testosterone. Knee laxity was measured as the amount of anterior tibial displacement at 133 N, using a standard knee arthrometer. To evaluate the relationship of knee laxity to changes in sex hormone concentrations, a multiple linear regression model with the possibility of a time delay was performed on each individual subject and the group as a whole. RESULTS: Individual regression equations revealed an average of 63% of the variance in knee laxity was explained by the three hormones and their interactions. All three hormones significantly contributed to the prediction equation, and the amount of variance explained was substantially greater when a time delay was considered. On average, knee laxity changed approximately 3, 4, and 4.5 d after changes in estradiol, progesterone, and testosterone, respectively. When females were analyzed as a group, only 8% of the variance in knee laxity was explained by sex-hormones levels. CONCLUSION: Changes in sex hormones mediate changes in knee laxity across the menstrual cycle. However, the strength of this relationship, the relative contribution of each hormone, and the associated time delay are highly variable between women. This individual variability is consistent with the variability in menstrual cycle characteristics among women.