Metal-free direct arylations of indoles and pyrroles with diaryliodonium salts.

Direct arylations of indoles and pyrroles with differently substituted diaryliodonium salts were shown to efficiently proceed in the absence of metal catalysts.

Palladium- and nickel-catalyzed aminations of aryl imidazolylsulfonates and sulfamates.

A nickel complex derived from dppf, along with NaOt-Bu as the base, allowed for challenging aminations of aryl sulfamates. An improved functional group tolerance is observed in novel palladium-catalyzed aminations of imidazolylsulfonates with rac-BINAP as the ligand.

Two titanium-catalyzed reaction sequences for syntheses of pyrroles from (E/Z)-chloroenynes or alpha-haloalkynols.

Titanium-catalyzed intermolecular hydroaminations of (E/Z)-chloroenynes enabled an efficient pyrrole synthesis, which set the stage for the development of a user-friendly one-pot reaction for the regioselective preparation of fully substituted pyrroles from easily accessible alpha-haloalkynols.