Comparison of Two Different Intervals of Misoprostol Administration in Second Trimester Abortions.

Objective: Comparison of two different intervals of misoprostol administration after mifepristone in second trimester abortions. Materials and methods: This 12-month prospective study was conducted at a tertiary care facility. Only pregnancies with congenital deformity or sterilisation failure were included in the study's recruitment of 100 women who visited the hospital for a second trimester abortion between 12 and 20 weeks; cases with scarred uteri were omitted. In a systematic random selection of 50 women in each group, the administration of 200 mg of mifepristone orally was followed by two distinct intervals of intravaginal misoprostol administration at 24- and 48-hour intervals. After 24 hours, group A women received intravaginal 400 mcg misoprostol three hourly, up to a maximum of five doses, while group B received the same doses after 48 hours. Induction abortion interval noted on various parameters and paired t test and chi square test applied. Results: The mean IAI following misoprostol administration was 8.14 2±.03 hours in group A and 7.71 ±2.56 hours in group B. This difference was statistically insignificant. Average misoprostol doses for group A were 1.68±0.71 and for the group, B were 1.68±0.84; both doses were found to be statistically insignificant when used to induce abortion. All women aborted successfully in each group. There was no significant difference in side effects in both groups. Conclusion: Based on the results it was observed that shorter interval between mifepristone and misoprostol i.e., 24 hours can be chosen to decrease the hospital stay as there was no significant difference was seen after intravaginal misoprostol in terms of induction abortion interval, number of doses and side effects.

Successful twin pregnancy in a unicornuate uterus with one fetus in the non-communicating rudimentary horn.

Rudimentary horn is a rare anomaly and results from arrested development of the mullerian ducts. We report a case of twin pregnancy in a unicornuate uterus with a non-communicating rudimentary horn, in which two siblings each in separate horn were delivered successfully by caesarean section.

Puerperal uterine inversion associated with unicornuate uterus.

Twenty-year-old para 1 presented with acute puerperal uterine inversion. Manual reposition and O'sullivan methods were tried but failed. She refused for any other corrective procedure. She again presented after 10 months with chronic puerperal inversion. Haultain operation was done. At laparotomy, inverted uterus was unicornuate, right kidney and ureter were absent.

Isthmic uterine fibroids: the dynamics of growth.

The isthmus of uterus is different from the rest of uterus and cervix in anatomic as well as functional aspects. The tumors arising from it may be subjected to a different set of forces which may predispose to growth in a tangential or horizontal direction. A young woman who underwent myomectomy for a large isthmic myoma is presented and the growth dynamics are discussed.

Primary leiomyosarcoma of broad ligament: case report and review of literature.

INTRODUCTION: Primary leiomyosarcoma of the broad ligament (LBL) is a very rare and highly malignant gynecological tumor. MATERIALS AND METHODS: A 45 year old hysterectomized woman with this rare tumor is presented. Treatment consisted of resection of the tumor along with omental and peritoneal sampling and adjuvant chemotherapy. No evidence of metastasis was present after 15 months of follow up. CONCLUSION: Complete surgery along with adjuvant chemotherapy or radiation and a close follow up for recurrence are advocated to optimize disease free survival.