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Clin Exp Obstet Gynecol ; 43(4): 509-511, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-29734537

RESUMO

OBJECTIVE: The aim of the study was to evaluate the value of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) to predict single-dose methotrexate (MTX) treatment success in ectopic pregnancy (EP). MATERIALS AND METHODS: A total of 115 EP diagnosed and hemodynamically stable women were enrolled in the study and divided into two groups as group 1, the treatment success group (n= 78) and group 2, the treatment failure group (n = 37). The authors compared the groups in terms of MPV and NLR. RESULTS: MPV and NLR levels were higher in MTX treatment successful group than in failure group.The cut-off values of MPV and NLR were determined as 10.1 fL and 1.82, respectively. These cut off values showed similar sensitivity and specificity in prediction of MTX treat- ment success. CONCLUSION: MPV and NLR can be used as reliable markers to predict single-dose MTX treatment success however further studies are needed.


Assuntos
Abortivos não Esteroides/administração & dosagem , Metotrexato/administração & dosagem , Gravidez Ectópica/sangue , Gravidez Ectópica/tratamento farmacológico , Gravidez Tubária/sangue , Gravidez Tubária/tratamento farmacológico , Adulto , Biomarcadores/sangue , Feminino , Humanos , Contagem de Linfócitos , Linfócitos , Volume Plaquetário Médio , Neutrófilos , Gravidez , Sensibilidade e Especificidade , Resultado do Tratamento
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