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1.
Bull Tokyo Dent Coll ; 56(3): 169-75, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26370577

RESUMO

Calcium deposited within a root canal due to exogenous stimuli may hamper root canal treatment. In endodontic treatment, an operating microscope allows the conditions within the root canal to be directly viewed and evaluated. This report describes a case in which an operating microscope was used to facilitate the excision of a calcified structure from within a root canal at an early stage in the treatment of an infection. An 18-year-old man was referred to our clinic due to suspected chronic suppurative apical periodontitis of the right maxillary central incisor. Periapical radiography confirmed the presence of a radioopaque structure inside the root canal that was likely to pose an obstacle to endodontic treatment. After opening the pulp chamber, an operating microscope was used to directly confirm the presence of the calcified structure in the root canal, which was removed using an ultrasonic tip. The infected root canal was treated using calcium hydroxide. Two months later, closure of the apical foramen as a result of calcification of the apical foramen was confirmed and the root canal filled. Using an operating microscope to directly view a structure posing an obstacle to root canal treatment made it possible to perform an excision while avoiding risks such as canal perforation.


Assuntos
Calcinose , Cavidade Pulpar/microbiologia , Irrigantes do Canal Radicular/uso terapêutico , Tratamento do Canal Radicular , Adolescente , Endodontia , Humanos , Infecções/tratamento farmacológico , Masculino , Periodontite Periapical/tratamento farmacológico , Ápice Dentário
2.
PLoS One ; 8(1): e54312, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23372703

RESUMO

The Fukushima Daiichi Nuclear Power Plant (FNPP) accident released large amounts of radioactive substances into the environment. In order to provide basic information for biokinetics of radionuclides and for dose assessment of internal exposure brought by the FNPP accident, we determined the activity concentration of radionuclides in the organs of 79 cattle within a 20-km radius around the FNPP. In all the specimens examined, deposition of Cesium-134 ((134)Cs, half-life: 2.065 y) and (137)Cs (30.07 y) was observed. Furthermore, organ-specific deposition of radionuclides with relatively short half-lives was detected, such as silver-110m ((110m)Ag, 249.8 d) in the liver and tellurium-129m ((129m)Te, 33.6 d) in the kidney. Regression analysis showed a linear correlation between the radiocesium activity concentration in whole peripheral blood (PB) and that in each organ. The resulting slopes were organ dependent with the maximum value of 21.3 being obtained for skeletal muscles (R(2) = 0.83, standard error (SE) = 0.76). Thus, the activity concentration of (134) Cs and (137)Cs in an organ can be estimated from that in PB. The level of radioactive cesium in the organs of fetus and infants were 1.19-fold (R(2) = 0.62, SE = 0.12), and 1.51-fold (R(2) = 0.70, SE = 0.09) higher than that of the corresponding maternal organ, respectively. Furthermore, radiocesium activity concentration in organs was found to be dependent on the feeding conditions and the geographic location of the cattle. This study is the first to reveal the detailed systemic distribution of radionuclides in cattle attributed to the FNPP accident.


Assuntos
Animais Recém-Nascidos/metabolismo , Radioisótopos de Césio/farmacocinética , Feto/metabolismo , Acidente Nuclear de Fukushima , Prata/farmacocinética , Telúrio/farmacocinética , Animais , Bovinos , Meio Ambiente , Feminino , Meia-Vida , Rim/química , Leucócitos Mononucleares/química , Fígado/química , Masculino , Músculo Esquelético/química , Centrais Nucleares , Gravidez , Radioisótopos
3.
Chem Commun (Camb) ; (13): 1384-5, 2002 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-12125567

RESUMO

A toxin and related compounds were isolated from a poisonous mushroom Tricholoma ustale. Their structures were determined by analyses of the spectral data and synthesis.


Assuntos
Agaricales/química , Micotoxinas/química , Micotoxinas/isolamento & purificação , Animais , Cromatografia em Gel , Cromatografia Líquida de Alta Pressão , Humanos , Espectroscopia de Ressonância Magnética , Camundongos , Estrutura Molecular
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