RESUMO
In this study the authors' purpose was to observe the effects of surgical stress on the number of lymphocyte beta-adrenergic receptors in hypertensive and normotensive subjects. It was noticed that after surgery a significant reduction occurred in the number of binding sites of lymphocytes of both hypertensive and normotensive subjects. The time course of recovery to the pre-operative values of binding sites varied between the two groups, being slower in normotensive than in hypertensive patients. This might suggest a different pattern of regulation of the beta-adrenergic receptor between hypertensive and normotensive subjects.
Assuntos
Linfócitos/metabolismo , Receptores Adrenérgicos beta/metabolismo , Estresse Fisiológico/metabolismo , Adulto , Idoso , Anestesia , Membrana Celular/metabolismo , Di-Hidroalprenolol , Feminino , Humanos , Hipertensão/sangue , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos OperatóriosAssuntos
Anestesia Intravenosa/efeitos adversos , Anestésicos/efeitos adversos , Hipersensibilidade a Drogas , Idoso , Espasmo Brônquico/induzido quimicamente , Toxidermias/etiologia , Hipersensibilidade a Drogas/etiologia , Hipersensibilidade a Drogas/prevenção & controle , Feminino , Humanos , Hipotensão/induzido quimicamente , Masculino , Pessoa de Meia-Idade , Insuficiência Respiratória/induzido quimicamenteRESUMO
Following mention of problems of cerebral haemodynamics and the action of various anaesthetics on endocranial pressure, a personal anaesthesiological technique based on the use of althesin in drip form is reported and its advantages listed.