Prevalência de atendimentos às vítimas de acidentes de trânsito durante a pandemia de COVID-19 / Prevalence of care for road traffic accident victims during the COVID-19 pandemic

Objetivo: Analisar a prevalência de acidentes de trânsito atendidos em um hospital de referência de urgência e emergência, no contexto da pandemia de COVID-19. Métodos: Estudo transversal, com amostra de 364 adultos vítimas de acidentes de trânsito, com idade entre 18 a 60 anos, de ambos os sexos. Utilizou-se um formulário de caracterização sociodemográfica e as características do acidente para coletar os dados. As variáveis foram analisadas por meio da estatística descritiva, análise bivariada e pelo teste Exato de Fisher, com nível de significância de 5% (p<0,05). Resultados: Na amostra, observou-se predomínio de pacientes do sexo masculino (77,1%), motoristas (71,1%), envolvendo motocicleta (68,6%) e sem a utilização do equipamento de proteção (73,3%). As lesões predominantes nos acidentes foram as fraturas (70,8%). Conclusão: Apesar da prevalência de atendimentos de urgências às vítimas de acidentes de trânsito durante a pandemia de COVID-19 ter diminuído de 0,77% (2019) para 0,34% em 2020, percebeu-se que as variáveis ainda permaneceram predominantes. Logo, os achados compreendem uma ferramenta importante para as políticas de prevenção e promoção à saúde, visando a redução de mortes, lesões e incapacidades. Descritores: Acidentes de trânsito. Serviços médicos de emergência. Epidemiologia. COVID-19

Objective: To analyze the prevalence of traffic accidents attended at an urgent and emergency referral hospital, in the context of the COVID-19 pandemic. Methods: Cross-sectional study with a sample of 364 adult victims of traffic accidents, aged between 18 and 60 years, of both sexes. A sociodemographic characterization form and accident characteristics were used to collect data. The variables were analyzed using descriptive statistics, bivariate analysis, and Fisher's Exact test, with a significance level of 5% (p<0.05). Results: In the sample, there was a predominance of male patients (77.1%), drivers (71.1%), involving motorcycle (68.6%) and without the use of protective equipment (73.3%). The predominant injuries in accidents were fractures (70.8%). Conclusion:Although the prevalence of emergency care for traffic accident victims during the COVID-19 pandemic decreased from 0.77% (2019) to 0.34% in 2020, it was noticed that the variables still remained predominant. Therefore, the findings comprise an important tool for prevention and health promotion policies, aiming at reducing deaths, injuries and disabilities. Descriptors: Accidents, traffic. Emergency medical services. Epidemiology. COVID-19

Effects of the application of the amniotic membrane in the healing process of skin wounds in rats.

PURPOSE: To evaluate the efficacy of the application of the human amniotic membrane (HAM) on the inflammatory process, fibroblast proliferation, formation of collagenand reduction of skin wound areas in rats. METHODS: Thirty six rats were submitted to a surgical injury induction and divided into two groups (n = 18): group C (control) and T (treated with the HAM). The macroscopic evolution in the wound area and the histological characteristics of the skin samples were evaluated. RESULTS: The regression of the wound area was greater in group T. The histological analysis revealed a significant reduction (p < 0.05) in the inflammatory infiltrate in group T at all experimental periods compared with that in the control group. Furthermore, the group T presented a significant increase in the proliferation of fibroblasts at 14 and 21 days compared with group C (p < 0.05). Regarding the deposition of mature collagen fibers, there was an increase in the replacement of type III collagen by type I collagen in group T (p < 0.05). CONCLUSION: Treatment with the HAM reduced the healing time as well as the inflammatory responses, increased the proliferation of fibroblasts, and induced a higher concentration of mature collagen fibers.

Effects of the application of the amniotic membrane in the healing process of skin wounds in rats

Abstract Purpose: To evaluate the efficacy of the application of the human amniotic membrane (HAM) on the inflammatory process, fibroblast proliferation, formation of collagenand reduction of skin wound areas in rats. Methods: Thirty six rats were submitted to a surgical injury induction and divided into two groups (n = 18): group C (control) and T (treated with the HAM). The macroscopic evolution in the wound area and the histological characteristics of the skin samples were evaluated. Results: The regression of the wound area was greater in group T. The histological analysis revealed a significant reduction (p < 0.05) in the inflammatory infiltrate in group T at all experimental periods compared with that in the control group. Furthermore, the group T presented a significant increase in the proliferation of fibroblasts at 14 and 21 days compared with group C (p < 0.05). Regarding the deposition of mature collagen fibers, there was an increase in the replacement of type III collagen by type I collagen in group T (p < 0.05). Conclusion: Treatment with the HAM reduced the healing time as well as the inflammatory responses, increased the proliferation of fibroblasts, and induced a higher concentration of mature collagen fibers.