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1.
Chaos ; 34(5)2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38780437

RESUMO

Floods significantly impact the well-being and development of communities. Hence, understanding their causes and establishing methodologies for risk prevention is a critical challenge for effective warning systems. Complex systems such as hydrological basins are modeled through hydrological models that have been utilized to understand water recharge of aquifers, available volume of dams, and floods in diverse regions. Acquiring real-time hydrometeorological data from basins and rivers is vital for establishing data-driven-based models as tools for the prediction of river-level dynamics and for understanding its nonlinear behavior. This paper introduces a hydrological model based on a multilayer perceptron neural network as a useful tool for time series modeling and forecasting river levels in three stations of the Rio Negro basin in Uruguay. Daily time series of river levels and rainfall serve as the input data for the model. The assessment of the models is based on metrics such as the Nash-Sutcliffe coefficient, the root mean square error, percent bias, and volumetric efficiency. The outputs exhibit varying model performance and accuracy during the prediction period across different sub-basin scales, revealing the neural network's ability to learn river dynamics. Lagged time series analysis demonstrates the potential for chaos in river-level time series over extended time periods, mainly when predicting dam-related scenarios, which shows physical connections between the dynamical system and the data-based model such as the evolution of the system over time.

2.
Infect Dis Model ; 9(1): 142-157, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38268698

RESUMO

The study of the propagation of infectious diseases in urban centers finds a close connection with their population's social characteristics and behavior. This work performs a spatial analysis of dengue cases in urban centers based on the basic reproduction numbers, R0, and incidence by planning areas (PAs), as well as their correlations with the Human Development Index (HDI) and the number of trips. We analyzed dengue epidemics in 2002 at two Brazilian urban centers, Belo Horizonte (BH) and Rio de Janeiro (RJ), using PAs as spatial units. Our results reveal heterogeneous spatial scenarios for both cities, with very weak correlations between R0 and both the number of trips and the HDI; in BH, the values of R0 show a less spatial heterogeneous pattern than in RJ. For BH, there are moderate correlations between incidence and both the number of trips and the HDI; meanwhile, they weakly correlate for RJ. Finally, the absence of strong correlations between the considered measures indicates that the transmission process should be treated considering the city as a whole.

3.
PLoS One ; 16(3): e0248126, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33690694

RESUMO

Topological analysis and community detection in mobility complex networks have an essential role in many contexts, from economics to the environmental agenda. However, in many cases, the dynamic component of mobility data is not considered directly. In this paper, we study how topological indexes and community structure changes in a business day. For the analyzes, we use a mobility database with a high temporal resolution. Our case study is the city of São José dos Campos (Brazil)-the city is divided into 55 traffic zones. More than 20 thousand people were asked about their travels the day before the survey (Origin-Destination Survey). We generated a set of graphs, where each vertex represents a traffic zone, and the edges are weighted by the number of trips between them, restricted to a time window. We calculated topological properties, such as degree, clustering coefficient and diameter, and the network's community structure. The results show spatially concise community structures related to geographical factors such as highways and the persistence of some communities for different timestamps. These analyses may support the definition and adjustment of public policies to improve urban mobility. For instance, the community structure of the network might be useful for defining inter-zone public transportation.


Assuntos
Dinâmica Populacional/estatística & dados numéricos , Meios de Transporte/estatística & dados numéricos , População Urbana/tendências , Algoritmos , Brasil , Cidades , Análise por Conglomerados , Gerenciamento de Dados , Humanos , Modelos Teóricos , Dinâmica Populacional/tendências
4.
PeerJ ; 8: e10287, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33194438

RESUMO

We present a robustness analysis of an inter-cities mobility complex network, motivated by the challenge of the COVID-19 pandemic and the seek for proper containment strategies. Brazilian data from 2016 are used to build a network with more than five thousand cities (nodes) and twenty-seven states with the edges representing the weekly flow of people between cities via terrestrial transports. Nodes are systematically isolated (removed from the network) either at random (failures) or guided by specific strategies (targeted attacks), and the impacts are assessed with three metrics: the number of components, the size of the giant component, and the total remaining flow of people. We propose strategies to identify which regions should be isolated first and their impact on people mobility. The results are compared with the so-called reactive strategy, which consists of isolating regions ordered by the date the first case of COVID-19 appeared. We assume that the nodes' failures abstract individual municipal and state initiatives that are independent and possess a certain level of unpredictability. Differently, the targeted attacks are related to centralized strategies led by the federal government in agreement with municipalities and states. Removing a node means completely restricting the mobility of people between the referred city/state and the rest of the network. Results reveal that random failures do not cause a high impact on mobility restraint, but the coordinated isolation of specific cities with targeted attacks is crucial to detach entire network areas and thus prevent spreading. Moreover, the targeted attacks perform better than the reactive strategy for the three analyzed robustness metrics.

5.
PLoS Comput Biol ; 7(5): e1001131, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21573202

RESUMO

This paper proposes a new method to identify communities in generally weighted complex networks and apply it to phylogenetic analysis. In this case, weights correspond to the similarity indexes among protein sequences, which can be used for network construction so that the network structure can be analyzed to recover phylogenetically useful information from its properties. The analyses discussed here are mainly based on the modular character of protein similarity networks, explored through the Newman-Girvan algorithm, with the help of the neighborhood matrix . The most relevant networks are found when the network topology changes abruptly revealing distinct modules related to the sets of organisms to which the proteins belong. Sound biological information can be retrieved by the computational routines used in the network approach, without using biological assumptions other than those incorporated by BLAST. Usually, all the main bacterial phyla and, in some cases, also some bacterial classes corresponded totally (100%) or to a great extent (>70%) to the modules. We checked for internal consistency in the obtained results, and we scored close to 84% of matches for community pertinence when comparisons between the results were performed. To illustrate how to use the network-based method, we employed data for enzymes involved in the chitin metabolic pathway that are present in more than 100 organisms from an original data set containing 1,695 organisms, downloaded from GenBank on May 19, 2007. A preliminary comparison between the outcomes of the network-based method and the results of methods based on Bayesian, distance, likelihood, and parsimony criteria suggests that the former is as reliable as these commonly used methods. We conclude that the network-based method can be used as a powerful tool for retrieving modularity information from weighted networks, which is useful for phylogenetic analysis.


Assuntos
Enzimas/química , Redes e Vias Metabólicas , Modelos Biológicos , Filogenia , Algoritmos , Sequência de Aminoácidos , Archaea/enzimologia , Archaea/fisiologia , Bactérias/metabolismo , Fenômenos Fisiológicos Bacterianos , Teorema de Bayes , Quitina/metabolismo , Quitina Sintase/química , Biologia Computacional , Bases de Dados Genéticas , Células Eucarióticas/enzimologia , Células Eucarióticas/fisiologia , Transdução de Sinais
6.
Biosystems ; 101(1): 59-66, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20420881

RESUMO

Chitin is a structural endogenous carbohydrate, which is a major component of fungal cell walls and arthropod exoskeletons. A renewable resource and the second most abundant polysaccharide in nature after cellulose, chitin is currently used for waste water clearing, cosmetics, medical, and veterinary applications. This work comprises data mining of protein sequences related to the chitin metabolic pathway of completely sequenced genomes of extant organisms pertaining to the three life domains, followed by meta-analysis using traditional sequence similarity comparison and complex network approaches. Complex networks involving proteins of the chitin metabolic pathway in extant organisms were constructed based on protein sequence similarity. Several usual network indices were estimated in order to obtain information on the topology of these networks, including those related to higher order neighborhood properties. Due to the assumed evolutionary character of the system, we also discuss issues related to modularity properties, with the concept of edge betweenness playing a particularly important role in our analysis. Complex network approach correctly identifies clusters of organisms that belong to phylogenetic groups without any a priori knowledge about the biological features of the investigated protein sequences. We envisage the prospect of using such a complex network approach as a high-throughput phylogenetic method.


Assuntos
Archaea/metabolismo , Bactérias/metabolismo , Quitina/metabolismo , Eucariotos/metabolismo , Modelos Biológicos , Proteínas/química , Proteínas/metabolismo , Transdução de Sinais/fisiologia , Sequência de Aminoácidos , Simulação por Computador , Dados de Sequência Molecular , Homologia de Sequência de Aminoácidos , Especificidade da Espécie
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