RESUMO
Sorghum, a gluten-free carbohydrate source with high antioxidants and resistant starch, contains anti-nutrients like phytic acid, tannin, and kafirin. Interactions with starch and proteins result in polyphenol-starch, starch-kafirin, and tannin-protein complexes. These interactions yield responses such as V-type amylose inclusion complexes, increased hydrophobic residues, and enzyme resistance, reducing nutrient availability and elevating resistant starch levels. Factors influencing these interactions include starch composition, structure, and Chain Length Distribution (CLD). Starch structure is impacted by enzymes like ADP-glucose pyrophosphorylase, starch synthases, and debranching enzymes, leading to varied chain lengths and distributions. CLD differences significantly affect crystallinity and physicochemical properties of sorghum starch. Despite its potential, the minimal utilization of sorghum starch in food is attributed to anti-nutrient interactions. Various modification approaches, either direct or indirect, offer diverse physicochemical changes with distinct advantages and disadvantages, presenting opportunities to enhance sorghum starch applications in the food industry.
RESUMO
Introduction: Automotive body painters are at risk of excessive lead exposure that may compromise their health. This study examined the protective effects of masks against lead exposure and its correlation with blood profile of automotive body painters at Ligu district, Semarang, Indonesia. Material and Methods: This cross-sectional study included 61 painters at Ligu district, Semarang, Indonesia (mean age 45 years, 100% male). Mask use was categorized into "frequent" and "infrequent". Blood samples were taken to measure lead exposure and haematological parameters (haemoglobin/HGB, erythrocytes/RBC, haematocrit/HCT, mean corpuscular haemoglobin/MCH, mean corpuscular volume/MCV, mean corpuscular haemoglobin concentration/MCHC). Effectivity of mask use against lead exposure was analysed with Fisher's exact test, while lead exposure and haematopoietic parameters were evaluated with Pearson's correlation tests. Results: There were 26 automotive painters (42.6%) classified as unfrequent mask users, and all of them had high blood lead levels. Most haematopoiesis parameters were in normal range. Workers with infrequent mask use were 1.269 more likely to be exposed to lead compared to those with frequent mask use (CI 95%, 1.082-1.552). Significant associations were found between lead exposure and RBC (p=0.0, r=-0.53), HGB (p=0, r=-0.61), and HCT (p=0.00, r=-0.61). No significant correlations were observed between lead exposure and MCV, MCH, MCHC. Conclusion: Lead exposure was significantly associated with haematological parameters RBC, HGB, and HCT, confirming the effects of prolonged exposure on blood profile. However, mask use provided significant protection against lead exposure in automotive body painters and should be an obligatory gear for workers.