Behavior of inflammatory markers of myocardial injury in cardiac surgery: laboratory correlation with the clinical picture of postpericardiotomy syndrome.

OBJECTIVE: To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. METHODS: This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demographic variables (sex and age), surgical variables (type and duration, extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflammatory response. RESULTS: Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not significantly different between the 2 assessed groups. No significant difference existed regarding either surgery duration or extracorporeal circulation. CONCLUSION: The patients who met the clinical criteria for postpericardiotomy syndrome were significantly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorporeal circulation.

Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca: correlaçäo laboratorial com quadro clínico de síndrome pós-pericardiotomia / Behavior of inflammatory markers of myocardial injury in cardiac surgery: laboratory correlation with the clinical picture of postpericardiotomy syndrome

OBJECTIVE: To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. METHODS: This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demographic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflammatory response. RESULTS: Of all patients, 12 (12.5 percent) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not significantly different between the 2 assessed groups. No significant difference existed regarding either surgery duration or extracorporeal circulation. CONCLUSION: The patients who met the clinical criteria for postpericardiotomy syndrome were significantly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorporeal circulation

Diagnostico da tricomonose urogenital pelo teste da imunofluorescencia indireta / Diagnostic of urogenital trichomonosis by the indirect fluoreccence antibody test

m diagnostico da tricomonoses urogenital e realizado pelo encontro do protozoario parasita atraves da microscopia de esfregaços a fresco e pelo exame cultual. Entretanto, nenhum destes procedimentos e indicado para estudo soroepidemiologicos e para a pesquisa de portadores assintomaticos. O teste da imunofluorescencia indireta (IFI) foi realizado em 200 mulheres pacientes de uma clinica de tratamento e controle de doenças sexualmente transmissiveis. Anticorpos anti-Trichomonas foram detectodos em 100% das pacvientes com tricomonose comprovada, emquanto que as mais alta diluiçao na qual os anticorpos foram demonstrados foi 1:80. Estes resultados sugerem que o teste da IFI pode ser util no aperfeicoamento do diagnostico

Diagnostico de laboratorio da criptosporidiose humana / Laboratory diagnostic of human cryptosporidiosis

No presente estudo sobre criptosporidiose humana sao apresentados os seus aspectos clinicos e descritos os metodos de laboratorio de diagnostico parasitologico e imunologico.

Laboratory diagnosis of Trichomonas vaginalis among women attending a venereal diseases control division. First report

El estudio presente fue efectuado con el objeto de determinar la incidencia de infecciones por Trichomonas vaginales asociadas a otras enfermedades venéreas. Fuerron investigadas 200 mujeres con este objeto tomando en cuenta su historia clínica, examen físico y examen en fresco, asi como cultivo. El parásito fue fue demonstrado 75 (37,5%) de 200 mujeres. También fueran relizadas pruebas para el diagnóstico de Candida albicans, Corynebacterium vaginales y Treponema pallidum