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2.
Biol Neonate ; 38(3-4): 134-8, 1980.
Artigo em Inglês | MEDLINE | ID: mdl-7407272

RESUMO

318 newborn babies were studied at term and after various complications of pregnancy or delivery for serum total bilirubin, alkaline phosphatase (ALP), asparate aminotransferase (AST), alanine aminotransferase (ALT) and glucose-6-phosphate dehydrogenase (G-6-PD). The total bilirubin levels tended to be lower in infants born after various complications of pregnancy or delivery than at term. The mean activity of ALP in the infants was not different from that of normal adults. Its activity decreased by the 5th day of life and was lower in the fetal distress group. The AST activity was much wider than the adult range but ALT activity did not differ from the adult level.


Assuntos
Alanina Transaminase/sangue , Fosfatase Alcalina/sangue , Aspartato Aminotransferases/sangue , Bilirrubina/sangue , Glucosefosfato Desidrogenase/sangue , Recém-Nascido , Apresentação Pélvica , Feminino , Sofrimento Fetal/sangue , Humanos , Recém-Nascido Prematuro , Complicações do Trabalho de Parto/sangue , Gravidez , Complicações na Gravidez/sangue , Valores de Referência
6.
Enzyme ; 22(4): 256-61, 1977.
Artigo em Inglês | MEDLINE | ID: mdl-18340

RESUMO

Influence of Isatin on rat tissue acid phosphatase has been studied. It has an organ-specific effect, the liver enzyme is activated, the brain enzyme is inhibited while those of kidney and intestine are not affected. Isatin activation of the liver enzyme is of mixed type and pH dependent. Rat liver enzyme appears to require intact amino and sulfhydryl groups for activity. Isatin seems to combine with the enzyme through the sulfhydryl group of the latter.


Assuntos
Fosfatase Ácida/metabolismo , Indóis/farmacologia , Isatina/farmacologia , Fígado/enzimologia , Animais , Encéfalo/enzimologia , Cisteína/farmacologia , Ativação Enzimática/efeitos dos fármacos , Concentração de Íons de Hidrogênio , Intestinos/enzimologia , Iodo/farmacologia , Iodoacetatos/farmacologia , Rim/enzimologia , Cinética , Masculino , Mercaptoetanol/farmacologia , Especificidade de Órgãos , Ratos
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