RESUMO
Acrodermatitis enteropathica syndrome (AE) is a clinical entity that results in severe zinc deficiency. It can be genetic or acquired. Acquired AE has been reported in patients with chronic liver disease, malabsorption syndrome, sickle cell anemia, and chronic renal failure. We present a kidney transplant recipient with skin rash and watery diarrhea. The patient had low serum zinc levels, which quickly resolved after zinc supplementation. Skin biopsy showed cytoplasmic pallor and vacuolization and ballooning degeneration of keratinocytes within the superficial epidermis, which may have led to confluent necrosis of keratinocytes. Large amounts of keratinosome-derived lamellae were found in the intercellular spaces in the keratinized area, probably related to disturbance of keratinosome metabolism due to zinc deficiency.
Assuntos
Acrodermatite/etiologia , Transplante de Rim/efeitos adversos , Zinco/deficiência , Acrodermatite/tratamento farmacológico , Acrodermatite/patologia , Fármacos Dermatológicos/uso terapêutico , Diarreia/etiologia , Epiderme/patologia , Dermatoses do Pé/tratamento farmacológico , Dermatoses do Pé/etiologia , Dermatoses do Pé/patologia , Dermatoses da Mão/tratamento farmacológico , Dermatoses da Mão/etiologia , Dermatoses da Mão/patologia , Humanos , Queratinócitos/patologia , Falência Renal Crônica/cirurgia , Masculino , Adulto Jovem , Zinco/uso terapêuticoRESUMO
Four-wave mixing from composite artificial Kerr media consisting of ellipsoidal microparticles suspended in a host liquid is discussed. Calculations of nonlinear grating formation and decay times are given in a dynamic model that includes the effect of random collisions on the particulates. Phase-conjugate efficiencies for a model configuration are given as well as operating limits imposed by particulate scattering from the composite.
RESUMO
Two sensitive differential optical techniques useful for study of small reflectance or absorptive differences between two interfaces are described. The first scheme employs a mechanically chopped light beam impinging on an arrangement of symmetrical dual cells to allow detection of differential reflectances DeltaR/R<10(-3). The second is a polarization-modulated beam-split laser version of the same method yielding approximately the same sensitivity. Representative measurements of voltage-induced reflectance changes at liquid-solid interfaces using these methods are given.
