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1.
Zh Mikrobiol Epidemiol Immunobiol ; (12): 62-4, 1985 Dec.
Artigo em Russo | MEDLINE | ID: mdl-3004073

RESUMO

Serum samples obtained from 44 patients with virus A hepatitis, 23 patients with virus B hepatitis, 65 patients with virus non A, non B hepatitis and 100 healthy adults were studied for the presence of Epstein-Barr (EB) virus in the indirect immunofluorescence test. In this work lymphoblastoid cell lines PH3-J-1 and CN37 were used. Among patients with different forms of hepatitis, the statistically significant elevation of the titers of antibodies to EB virus was detected only in the group of patients with virus non A, non B hepatitis, and in 6 cases the etiological role of EB virus was confirmed by serological and hematological methods.


Assuntos
Anticorpos Antivirais/análise , Hepatite Viral Humana/imunologia , Herpesvirus Humano 4/imunologia , Doença Aguda , Adolescente , Adulto , Capsídeo/imunologia , Criança , Hepatite A/imunologia , Hepatite B/imunologia , Antígenos de Superfície da Hepatite B/análise , Hepatite C/imunologia , Humanos , Mononucleose Infecciosa/imunologia
3.
Zh Mikrobiol Epidemiol Immunobiol ; (10): 45-9, 1979 Oct.
Artigo em Russo | MEDLINE | ID: mdl-315678

RESUMO

In lymphocyte cultures (LC) from 5 immune donors blast transformation occurred as a result of the stimulting action of adenovirus antigen; the supernatants obtained from these cultures produced a cytotoxic effect on L cells, thus suggesting the presence of lymphotoxin (LT). No blast transformation and no LT production were detected in nonstimulated LC used for control, as well as in LC from 9 nonimmune donors. LT production was shown to depend on the time elapsed after recovery from acute adenovirus infection. LT production was found to be most intensive during the first 2 months after recovery.


Assuntos
Adenovírus Humanos/imunologia , Antígenos Virais/imunologia , Linfócitos/imunologia , Linfotoxina-alfa/biossíntese , Doença Aguda , Infecções por Adenovirus Humanos/imunologia , Adulto , Animais , Criança , Doença Crônica , Citotoxicidade Imunológica , Humanos , Técnicas In Vitro , Células L/efeitos dos fármacos , Ativação Linfocitária , Camundongos , Tonsilite/imunologia
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