Therapeutic efficacy of isavuconazole and potassium iodide in a cat with refractory sporotrichosis.

A seven-month-old, male, domestic short-hair cat was presented with nodular and ulcerative lesions, as well as respiratory signs, caused by Sporothrix brasiliensis infection. Owing to lack of response to oral itraconazole and potassium iodide, isavuconazole was substituted for itraconazole, leading to clinical cure after three months of treatment without adverse effects.

Un chat domestique mâle à poil court de 7 mois est présenté avec des lésions nodulaires et ulcéreuses, ainsi que des signes respiratoires, causés par une infection à Sporothrix brasiliensis. En raison de l'absence de réponse à l'itraconazole oral et à l'iodure de potassium, l'isavuconazole est substitué à l'itraconazole, ce qui conduit à une guérison clinique après 3 mois de traitement sans effets indésirables.

Um gato doméstico de pelo curto de sete meses de idade foi apresentado com lesões nodulares e ulcerativas, bem como sintomas respiratórios, causados por infecção por Sporothrix brasiliensis. Devido à pobre resposta ao tratamento com itraconazol oral e iodeto de potássio, itraconazol foi substituído por isavuconazol, levando à cura clínica após três meses de tratamento, sem efeitos adversos.

Un gato doméstico de pelo corto, macho, de 7 meses de edad, se presentó con lesiones nodulares y ulcerativas, así como signos respiratorios, causados por infección por Sporothrix brasiliensis. Ante la falta de respuesta a itraconazol y yoduro potásico orales, se sustituyó itraconazol por isavuconazol, con curación clínica tras 3 meses de tratamiento sin efectos adversos.

Can We Reliably Detect Respiratory Diseases through Precision Farming? A Systematic Review.

Respiratory diseases commonly affect livestock species, negatively impacting animal's productivity and welfare. The use of precision livestock farming (PLF) applied in respiratory disease detection has been developed for several species. The aim of this systematic review was to evaluate if PLF technologies can reliably monitor clinical signs or detect cases of respiratory diseases. A technology was considered reliable if high performance was achieved (sensitivity > 90% and specificity or precision > 90%) under field conditions and using a reliable reference test. Risk of bias was assessed, and only technologies tested in studies with low risk of bias were considered reliable. From 23 studies included-swine (13), poultry (6), and bovine (4) -only three complied with our reliability criteria; however, two of these were considered to have a high risk of bias. Thus, only one swine technology fully fit our criteria. Future studies should include field tests and use previously validated reference tests to assess technology's performance. In conclusion, relying completely on PLF for monitoring respiratory diseases is still a challenge, though several technologies are promising, having high performance in field tests.