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J Infect Chemother ; 8(1): 99-102, 2002 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11957128

RESUMO

We report a 17-year-old man with destructive pulmonary embolism caused by Staphylococcus aureus bacteremia. The patient was not immunocompromised and had neither underlying diseases nor risk factors, such as concomitant influenza viral infection, which exacerbate staphylococcal infections. The rapid and extensive progression of pulmonary involvement in all lung fields make this a rare case; there have been few reports in the literature describing a similar radiographic appearance in patients with community-acquired staphylococcal bacteremia. In-vitro studies did not demonstrate the production of enterotoxins or toxic shock syndrome toxin 1 (TSST-1) by the isolated strain, but genetic analysis detected Panton-Valentine leukocidine gene from the strain. Subsequent empyema with bilateral pneumothorax was prolonged because of superinfection with both methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Optional surgical treatments, including thoracostomy and thoracopneumoplasty, finally improved his condition.


Assuntos
Bacteriemia/complicações , Toxinas Bacterianas , Infecções Comunitárias Adquiridas/complicações , Embolia Pulmonar/etiologia , Infecções Estafilocócicas/complicações , Superantígenos , Adolescente , Enterotoxinas/toxicidade , Exotoxinas , Humanos , Leucocidinas/biossíntese , Leucocidinas/genética , Masculino , Staphylococcus aureus
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