Severe ischemia of the hand following intra-arterial promazine injection: effects of vasodilation, anticoagulation, and local thrombolysis with tissue-type plasminogen activator.

Promazine hydrochloride was injected accidentally in the antecubital artery of a 42-year-old woman, resulting in severe ischemia of the second and third fingers of her right hand which lasted for four days before she was hospitalized. Vasodilation by combining axillary plexus block and intravenous sodium nitroprusside did not improve ischemia and local thrombolysis was performed using recombinant tissue-type plasminogen activator (50 mg over 8 hours), resulting in normalization of digital pressure in one of the two affected fingers. The outcome was favourable and amputation could be avoided.

[Invasive pulmonary aspergillosis associated with an acute influenza virus infection]. / Aspergillose pulmonaire invasive associée à une infection aiguë à virus influenza.

We report a fatal case of invasive pulmonary aspergilloma (API) in association with an influenza A virus infection, occurring in a patient without any factor generally associated with a lowering of immunocompetence. There are five cases in the literature associating these two infections: the immunosuppressive effect of the influenza virus is possibly responsible for the mycotic invasive mass often encountered in the immunosuppressed.