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Behav Neurosci ; 131(2): 149-154, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-28230385

RESUMO

The present experiment was designed to determine if the absence of an auditory cue (i.e., a "tone-off" cue) would be an effective conditioned stimulus (CS) for delay eyeblink conditioning and to test if the medial geniculate nucleus (MGN) is part of the sensory pathway for tone-off conditioning. Rats were given paired or unpaired delay eyeblink conditioning to examine if responding to a tone-off CS was due to an associative process. An inactivation technique was performed on a separate group of rats to determine if the MGN is needed to express tone-off conditioning. The results showed that rats given paired conditioning acquired robust conditioned eyeblink responses (CRs) compared with rats given unpaired conditioning and that expression of tone-off elicited CRs was impaired when the MGN was inactivated. The findings suggest that tone-on and tone-off eyeblink conditioning may share a common neural pathway. (PsycINFO Database Record


Assuntos
Estimulação Acústica , Aprendizagem por Associação , Condicionamento Palpebral , Sinais (Psicologia) , Corpos Geniculados/fisiologia , Animais , Aprendizagem por Associação/efeitos dos fármacos , Condicionamento Palpebral/efeitos dos fármacos , Agonistas de Receptores de GABA-A/administração & dosagem , Corpos Geniculados/efeitos dos fármacos , Masculino , Muscimol/administração & dosagem , Ratos , Ratos Long-Evans
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