Assuntos
Distonia/complicações , Taquicardia Ventricular/etiologia , Adolescente , Adulto , Fatores Etários , Distonia/fisiopatologia , Eletrocardiografia , Eletrocardiografia Ambulatorial , Feminino , Frequência Cardíaca , Humanos , Masculino , Análise Multivariada , Análise de Regressão , Sistema Nervoso Simpático/fisiopatologia , Síndrome , Taquicardia Ventricular/diagnóstico , Taquicardia Ventricular/fisiopatologiaRESUMO
A contribution of specific features of myocardial hypertrophy and hypercontractility left ventricular diastolic dysfunction to decreased exercise tolerance and developed coronary failure is discussed on the basis of results obtained from a bicycle ergometric test performed in 40 patients with hypertrophic cardiomyopathy. Thallium-201 myocardial scintigraphy conducted at the maximum exercise in 17 patients revealed a reduction in coronary reserve with increased myocardial mass index that was higher than the critical value. An implication of severe myocardial hypertrophy in the presence with coexisting left ventricular posterior wall hypertrophy and impaired perfusion/mass ratios is considered as a risk factor for death of patients with hypertrophic cardiomyopathy.
Assuntos
Cardiomiopatia Hipertrófica/fisiopatologia , Frequência Cardíaca/fisiologia , Contração Miocárdica/fisiologia , Resistência Física/fisiologia , Esforço Físico/fisiologia , Função Ventricular Esquerda/fisiologia , Adulto , Idoso , Cardiomiopatia Hipertrófica/diagnóstico por imagem , Ecocardiografia , Teste de Esforço , Humanos , Pessoa de Meia-Idade , Cintilografia , Radioisótopos de TálioAssuntos
Angina Pectoris/fisiopatologia , Cardiomiopatia Hipertrófica/fisiopatologia , Eletrocardiografia , Infarto do Miocárdio/fisiopatologia , Adulto , Cardiomiopatia Hipertrófica/diagnóstico , Cardiomiopatia Hipertrófica/tratamento farmacológico , Doença das Coronárias/diagnóstico , Doença das Coronárias/tratamento farmacológico , Diagnóstico Diferencial , Ecocardiografia , Humanos , Masculino , SíndromeRESUMO
The causes leading to the appearance of positive reactions in diagnostic titers (1:200 and higher), registered in the sera of healthy persons in tests carried out with the use of experimental and commercial lots of Shigella sonnei and Shigella flexneri antigenic diagnostic reagents, are analyzed. The study has shown that the appearance of nonspecific reactions may be due to the influence of the initial state of the microbial culture (the biomass used as raw material for the production of sensitin), the method of the isolation of the antigen and its sensitizing dose, the kind of the erythrocyte carrier, the method of erythrocyte fixation and the temperature conditions of the passive hemagglutination test. The ways for the elimination of positive seroconversions are outlined.
Assuntos
Antígenos/imunologia , Eritrócitos/imunologia , Animais , Antígenos de Bactérias/imunologia , Células Cultivadas , Galinhas/imunologia , Epitopos/imunologia , Cabras/imunologia , Humanos , Imunidade Inata , Técnicas Imunológicas , Ovinos/imunologia , Shigella flexneri/imunologia , Shigella sonnei/imunologia , Especificidade da EspécieRESUMO
Antigenous (antibody binding) activity in vitro and disaggregating (absolute and relative) activity of choriogonin in the urine were studied simultaneously during pregnancy by means of the serologic tests--antibody neutralization and red cell disaggregation. The time course of choriogonin activity in the urine, which reflects variations in the molecular parameters of choriogonin in pregnancy indicates that it may be detected in the urine in the form of isohormones. Variations in the molecular parameters of choriogonin during pregnancy differ from those in its antibody binding activity. Application of serodiagnostic approaches may be valuable in determining the time course of the molecular parameters of hormones.
