RESUMO
Possibility of application of the living tissues electric welding technologies in the treatment of varicose disease of lower extremities, using endovenous electric welding (EVEW) of large subcutaneous vein (LSV), was studied, its optimal parameters were determined. ÐVEW have provided effective impact on venous vessel, and guaranteed secure obliteration of LSV. The method may be used successfully in the treatment of varicose disease. Optimal parameters of EVEW, secure and safe in clinical conditions, were determined in experiment. Absence of negative impact of EVEW towards adjacent tissues have permitted to perform intervention without tumescent anesthesia. Further improvement and introduction of the EVEW method opens new possibilities for enhancing of quality of the varicose disease surgical treatment.
Assuntos
Ablação por Cateter/métodos , Eletrocoagulação/métodos , Procedimentos Endovasculares/métodos , Veia Safena/cirurgia , Varizes/cirurgia , Adulto , Idoso , Ablação por Cateter/instrumentação , Eletricidade , Eletrocoagulação/instrumentação , Procedimentos Endovasculares/instrumentação , Feminino , Humanos , Extremidade Inferior/irrigação sanguínea , Extremidade Inferior/patologia , Extremidade Inferior/cirurgia , Masculino , Pessoa de Meia-Idade , Ondas de Rádio , Veia Safena/patologia , Resultado do Tratamento , Varizes/patologiaRESUMO
The results of treatment of 58 patients, suffering chronic diseases of the lower extremities veins, were analyzed. In 28 patients a vertical reflux was eliminated using endovascular laser coagulation, in 32 patients--a standard phlebectomy in accordance to Babcock method was performed. The complications rate was compared as well as the term of the patients' stationary treatment. After elimination of endovascular laser coag- ulation the complications rate and severity is significantly lesser, than after a standard phiebectomy. In accordance to the ultrasonographic duplex scanning data in 12 mo in one patient a partial recanalization of large subcutaneous vein was noted. A total fibrous transformation of the coagulated venous trunks was achieved in 95.24% of the patients. Duration of postoperative stationary treatment have had reduced from (4.8 ± 0.8) to (1.2 ± 0.1) days (p < 0.001).
Assuntos
Procedimentos Endovasculares/métodos , Fotocoagulação a Laser/métodos , Complicações Pós-Operatórias/prevenção & controle , Veia Safena/cirurgia , Varizes/cirurgia , Insuficiência Venosa/cirurgia , Adulto , Idoso , Doença Crônica , Procedimentos Endovasculares/efeitos adversos , Procedimentos Endovasculares/instrumentação , Feminino , Hematoma/etiologia , Hematoma/patologia , Humanos , Fotocoagulação a Laser/efeitos adversos , Fotocoagulação a Laser/instrumentação , Extremidade Inferior/irrigação sanguínea , Extremidade Inferior/patologia , Extremidade Inferior/cirurgia , Masculino , Pessoa de Meia-Idade , Dor Pós-Operatória/etiologia , Dor Pós-Operatória/patologia , Parestesia/etiologia , Parestesia/patologia , Estudos Prospectivos , Veia Safena/patologia , Resultado do Tratamento , Ultrassonografia Doppler Dupla , Varizes/patologia , Insuficiência Venosa/patologiaRESUMO
Results of experimental investigation for studying of the local application possibility for the reparative processes stimulators, including autologic purified lipoaspirate, dalargin and a plateletrich plasma (PRP) for treatment of chronic gastric ulcers, were analyzed. The advantages of PRP application, as the growth factors donator, independently and in combination with dalargin, were proved. The PRP capacity to stimulate the fibroblasts activity and creation of vessels in young connective tissue was proved, what have leaded to the ulcer tissues oxygenation improvement and cellular proliferation promotion, acceleration of the connective tissue maturation, and the ulcer healing.
Assuntos
Anti-Inflamatórios não Esteroides/farmacologia , Misturas Complexas/farmacologia , Leucina Encefalina-2-Alanina/análogos & derivados , Peptídeos e Proteínas de Sinalização Intercelular/farmacologia , Plasma Rico em Plaquetas/química , Úlcera Gástrica/terapia , Tecido Adiposo/química , Animais , Proliferação de Células/efeitos dos fármacos , Doença Crônica , Misturas Complexas/isolamento & purificação , Modelos Animais de Doenças , Células Endoteliais/citologia , Células Endoteliais/efeitos dos fármacos , Leucina Encefalina-2-Alanina/farmacologia , Feminino , Fibroblastos/citologia , Fibroblastos/efeitos dos fármacos , Humanos , Lipectomia/métodos , Masculino , Consumo de Oxigênio/efeitos dos fármacos , Ratos , Ratos Wistar , Úlcera Gástrica/patologia , Cicatrização/efeitos dos fármacosRESUMO
The dynamics of cytopathic hypoxia markers in patients with acute pancreatitis (AP) biliary etiology (BE), depending on the presence of concomitant diabetes mellitus (DM), which is an independent factor of premorbid severity increase and increase in the degree of operational and anesthetic risk. Markers of cytopathic hypoxia use as methods for early diagnosis of acute liver failure (ALF) and monitoring the effectiveness of its correction promising. In terms of cytopathic hypoxia may be at the stage of laboratory diagnostics to distinguish between destructive and non-destructive forms APBE, and for markers of endothelial dysfunction--destructive forms on the area and depth of destruction of the pancreas.
