1.
Chem Commun (Camb)
; 51(53): 10648-51, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26051897
RESUMO
Cyclic amines such as pyrrolidine and 1,2,3,4-tetrahydroisoquinoline undergo redox-annulations with α,ß-unsaturated aldehydes and ketones. Carboxylic acid promoted generation of a conjugated azomethine ylide is followed by 6π-electrocylization, and, in some cases, tautomerization. The resulting ring-fused pyrrolines are readily oxidized to the corresponding pyrroles or reduced to pyrrolidines.