[Properties of Staphylococcus aureus in case of the unfavorable course of burn infection]. / Svoistva Staphylococcus aureus pri neblagopriiatnom techenii ozhogovoi infektsii.

Clinical and microbiological study of wound discharge from 35 patients demonstrated a relationship between biological properties of S. aureus, the causative agent of burn infection, and the course of the infected burn trauma. The prognostic importance of the antioxidant properties of these staphylococci was established: in cases of the unfavorable course of the burn process they showed essentially greater resistance to peroxinitrite and higher superoxide dismutase activity in comparison with the cultures isolated from patients with uncomplicated wound infection.

[Activity catalase and superoxide dismutase of Staphylococcus aureus during its persistence in the body]. / Aktivnost' katalazy i superoksiddismutazy Staphylococcus aureus pri ikh persistirovanii v organizme.

The dynamics of the level of catalase and superoxidedismutase (SOD) expression by S. aureus isolated in persistent experimental kidney infection is described. A rise in the activity of the staphylococci under study during transition of the infectious process from the alteration to persistence stage. Changes in the expression of SOD and catalase were observed simultaneously with a decrease in hemolytic, fibrinolytic and protease activity, as well as in the presence of more pronounced clumping and an increase in the production of protein A, the antilysozyme and anticomplement activity of staphylococcal clones obtained from kidney tissue. The significance of all above-mentioned phenomena in the persistence of microorganisms is discussed.